Acridine

Acridine

SCHEMBL10533085

N=C=O.N=C=O.c1ccc2nc3ccccc3cc2c1

nearest known ligand 0.71

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.71
HPGD P15428 3/20 0.71
MAPT P10636 3/20 0.71
GLA P06280 2/20 0.71
ACHE P22303 1/20 0.71
HTR3A P46098 1/20 0.52
NQO2 P16083 2/20 0.48
KMT2A Q03164 4/20 0.45
KDM4E B2RXH2 3/20 0.45
GAA P10253 3/20 0.45
RAB9A P51151 3/20 0.45
NPC1 O15118 3/20 0.45
POLB P06746 2/20 0.45
LMNA P02545 1/20 0.45
PTBP1 P26599 1/20 0.45
RCE1 Q9Y256 1/20 0.45
TDP1 Q9NUW8 1/20 0.42
STAT3 P40763 1/20 0.42
IKBKB O14920 1/20 0.41
PDE2A O00408 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acridine SCHEMBL28002752 1.00 ALDH1A1 (0.71) ALDH1A1HPGDMAPTGLAACHE
Acridine SCHEMBL1006962 0.86 ALDH1A1 (0.71) ALDH1A1HPGDMAPTGLAACHE
Acridine SCHEMBL37657 0.86 ALDH1A1 (0.71) ALDH1A1HPGDMAPTGLAACHE
Acridine SCHEMBL3045498 0.84 ALDH1A1 (1.00) ALDH1A1HPGDMAPTGLAACHE
Acridine SCHEMBL4972293 0.84 ALDH1A1 (1.00) ALDH1A1HPGDMAPTGLAACHE
Acridine SCHEMBL1772714 0.84 ALDH1A1 (1.00) ALDH1A1HPGDMAPTGLAACHE
Acridine SCHEMBL8339 0.84 ALDH1A1 (1.00) ALDH1A1HPGDMAPTGLAACHE
Acridine SCHEMBL29352289 0.84 ALDH1A1 (1.00) ALDH1A1HPGDMAPTGLAACHE
Acridine SCHEMBL28830169 0.82 MAPT (0.83) ALDH1A1HPGDMAPTGLAACHE
Anthracene SCHEMBL9879830 0.82 MAPT (0.94) ALDH1A1HPGDMAPTGLAACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4824824-A COLOR FORMING AROMATIC ISOCYANATES AND IMINE COMPOUNDS MITSUBISHI PAPER MILLS, LTD. (JP) 1989-04-25 US disclosed
EP-0101741-B1 COLORING METHOD AND COLOR-FORMING MATERIAL Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1987-05-20 EP disclosed
US-4521793-A Coloring method and color-forming material ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1985-06-04 US disclosed
EP-0101741-A1 COLORING METHOD AND COLOR-FORMING MATERIAL Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1984-03-07 EP disclosed