Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 3/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 7/20 | 0.35 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | GMNN | O75496 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | PIM1 | P11309 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.32 |
| ▸ | CCKBR | P32239 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8890261 | 0.89 | DHODH (0.33) | DHODHCYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL8899416 | 0.89 | DHODH (0.32) | DHODHPTGDR2HTR2AEPHX2 | |
| SCHEMBL8892498 | 0.87 | PTGDR2 (0.33) | DHODHPTGDR2KDM4C | |
| SCHEMBL8890320 | 0.86 | DHODH (0.43) | DHODHCYP3A4CYP2C9CYP2C19EPHX2 | |
| SCHEMBL8491851 | 0.85 | DHODH (0.47) | DHODHPTGDR2KDM4CMEN1KMT2A | |
| SCHEMBL8891126 | 0.84 | DHODH (0.41) | DHODHPTGDR2KDM4CMEN1KMT2A | |
| SCHEMBL8891898 | 0.83 | DHODH (0.41) | DHODHPTGDR2KDM4CMEN1KMT2A | |
| SCHEMBL8891280 | 0.83 | CYP19A1 (0.33) | DHODH | |
| SCHEMBL8891112 | 0.83 | TAS1R3 (0.35) | DHODHCYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL8893446 | 0.83 | DHODH (0.34) | DHODHCYP3A4SLC6A2EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997028136-A1 | BENZOYLISOXAZOLES AND 2-CYANO-1,3-DIONE DERIVATIVES AND THEIR USE AS HERBICIDES | RHONE-POULENC AGRICULTURE LTD. (GB) | 1997-08-07 | — | — | WO | disclosed |