Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 4/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
| ▸ | TRPM8 | Q7Z2W7 | 7/20 | 0.33 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.33 |
| ▸ | HSD17B13 | Q7Z5P4 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | CFD | P00746 | 1/20 | 0.32 |
| ▸ | KLK7 | P49862 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8890261 | 0.87 | DHODH (0.33) | DHODHEPHX2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL8891989 | 0.86 | DHODH (0.41) | DHODHEPHX2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL8899416 | 0.86 | DHODH (0.32) | DHODHEPHX2 | |
| SCHEMBL8890755 | 0.85 | DHODH (0.44) | DHODHEPHX2CYP11B1CYP11B2TRPM8 | |
| SCHEMBL8892498 | 0.84 | PTGDR2 (0.33) | DHODH | |
| SCHEMBL8890787 | 0.84 | DHODH (0.43) | DHODHEPHX2CYP11B1CYP11B2TRPM8 | |
| SCHEMBL8891280 | 0.81 | CYP19A1 (0.33) | DHODH | |
| SCHEMBL9116698 | 0.81 | DHODH (0.48) | DHODHEPHX2TRPM8NR1H4HSD17B13 | |
| SCHEMBL8891112 | 0.81 | TAS1R3 (0.35) | DHODHCYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL8891528 | 0.80 | PTGDR2 (0.36) | DHODHEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997028136-A1 | BENZOYLISOXAZOLES AND 2-CYANO-1,3-DIONE DERIVATIVES AND THEIR USE AS HERBICIDES | RHONE-POULENC AGRICULTURE LTD. (GB) | 1997-08-07 | — | — | WO | disclosed |