Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 4/20 | 0.51 |
| ▸ | FADS1 | O60427 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | AR | P10275 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2798690 | 0.87 | GRM2 (0.52) | GRM2FADS1ALDH1A1MAOAHDAC1 | |
| SCHEMBL7460584 | 0.87 | GRM2 (0.52) | GRM2FADS1ALDH1A1MAOAHDAC1 | |
| SCHEMBL7520181 | 0.80 | GRM2 (0.48) | GRM2FADS1ALDH1A1ARHDAC1 | |
| SCHEMBL7237979 | 0.76 | GRM2 (0.65) | GRM2MAOA | |
| SCHEMBL8948639 | 0.76 | GRM2 (0.65) | GRM2MAOA | |
| SCHEMBL8948817 | 0.76 | GRM2 (0.65) | GRM2MAOA | |
| SCHEMBL7465104 | 0.74 | EPHX2 (0.50) | GRM2ALDH1A1MAOAHDAC1HDAC8 | |
| SCHEMBL2798691 | 0.73 | GRM2 (0.65) | GRM2 | |
| SCHEMBL8316448 | 0.73 | GRM2 (0.65) | GRM2 | |
| SCHEMBL7457111 | 0.72 | ADORA2A (0.48) | GRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5614535-A | Adhesion receptor antagonists | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1997-03-25 | — | — | US | disclosed |