SCHEMBL8892298

SCHEMBL8892298

CC1(C)CC(NC(=O)CC#N)CC(C)(C)N1

nearest known ligand 0.54

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.54
KMT2A Q03164 3/20 0.50
HTT P42858 2/20 0.50
KDM4E B2RXH2 1/20 0.49
RECQL P46063 2/20 0.46
POLB P06746 2/20 0.46
MEN1 O00255 1/20 0.46
MAPT P10636 1/20 0.46
USP2 O75604 1/20 0.46
PKM P14618 1/20 0.44
L3MBTL1 Q9Y468 2/20 0.43
ATM Q13315 1/20 0.43
EZH2 Q15910 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2901212 0.80 GAA (0.71) GAAKMT2AHTTKDM4ERECQL
SCHEMBL8771939 0.79 GAA (0.59) GAAKMT2AHTTKDM4ERECQL
SCHEMBL29494819 0.77 GAA (0.58) GAAKMT2AHTTKDM4ERECQL
SCHEMBL28800695 0.77 GAA (0.58) GAAKMT2AHTTKDM4ERECQL
SCHEMBL6234624 0.77 GAA (0.58) GAAKMT2AHTTKDM4ERECQL
SCHEMBL10079252 0.77 GAA (0.58) GAAKMT2AHTTKDM4ERECQL
SCHEMBL9682135 0.77 GAA (0.58) GAAKMT2AHTTKDM4ERECQL
SCHEMBL1647940 0.77 GAA (0.67) GAAKMT2AHTTKDM4ERECQL
Diethylamine SCHEMBL4087150 0.77 GAA (0.54) GAAKMT2AHTTKDM4ERECQL
SCHEMBL4094277 0.76 GAA (0.65) GAAKMT2AHTTKDM4ERECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5624981-A Polyalkylpiperidine containing acetic acid and 3-amino-acrylic acid derivatives BASF AKTIENGESELLSCHAFT (DE) 1997-04-29 US disclosed
EP-0241419-B1 PIGMENTS CONTAINING PIPERIDYL GROUPS SANDOZ AG (CH) 1993-05-19 EP disclosed
US-5145966-A Heat resistance and photostability for polyamides BASF AKTIENGESELLSCHAFT (DE) 1992-09-08 US disclosed
EP-0422492-A1 Cyclic amides BASF Aktiengesellschaft (DE) 1991-04-17 EP disclosed
US-4866113-A COLORING POLYMERS SANDOZ LTD. (CH) 1989-09-12 US disclosed
US-4838943-A Compounds useful as pigments containing one or more 2,2,6,6-tetraalkylpiperidine groups SANDOZ LTD. (CH) 1989-06-13 US disclosed
EP-0241419-A2 Pigments containing piperidyl groups SANDOZ AG (CH) 1987-10-14 EP disclosed