Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | QPCT | Q16769 | 4/20 | 0.38 |
| ▸ | NAMPT | P43490 | 5/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HTR6 | P50406 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8891902 | 0.86 | SIGMAR1 (0.39) | LMNAALDH1A1KMT2ATSHR | |
| SCHEMBL8892577 | 0.84 | TACR1 (0.39) | MEN1KMT2A | |
| SCHEMBL8891331 | 0.82 | TACR1 (0.39) | LMNAMEN1KMT2ATSHR | |
| Bromide SCHEMBL8890170 | 0.81 | ALDH1A1 (0.37) | MAPTALDH1A1MEN1KMT2A | |
| Iodide SCHEMBL8891218 | 0.81 | TACR1 (0.36) | NAMPTMAPTMEN1KMT2A | |
| Bromide SCHEMBL8890802 | 0.79 | TACR1 (0.33) | ALDH1A1MEN1KMT2A | |
| Bromide SCHEMBL8891469 | 0.78 | TACR1 (0.35) | LMNAALDH1A1 | |
| Bromide SCHEMBL8891355 | 0.78 | ALDH1A1 (0.38) | ALDH1A1MEN1KMT2A | |
| Bromide SCHEMBL8890180 | 0.77 | TACR1 (0.38) | LMNAMAPTALDH1A1 | |
| SCHEMBL8890274 | 0.76 | TACR1 (0.42) | L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997005110-A1 | PERHYDROISOINDOLE DERIVATIVES AS SUBSTANCE P AND NEUROKININE A ANTAGONISTS | RHONE-POULENC RORER S.A. (FR) | 1997-02-13 | — | — | WO | disclosed |