Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BLM | P54132 | 2/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.45 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.43 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.43 |
| ▸ | PGR | P06401 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.43 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.43 |
| ▸ | SLC47A1 | Q96FL8 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | CCR1 | P32246 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 2/20 | 0.40 |
| ▸ | DRD4 | P21917 | 2/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8891230 | 0.84 | SMN1; SMN2 (0.43) | BLMCYP2D6SLC22A2SLC22A1PGR | |
| SCHEMBL1923867 | 0.83 | OPRM1 (0.54) | CYP2D6CCR1DRD2DRD4OPRM1 | |
| SCHEMBL8049521 | 0.81 | HDAC6 (0.49) | — | |
| SCHEMBL11471791 | 0.81 | CCR1 (0.46) | BLMCYP2D6SLC22A2SLC22A1PGR | |
| SCHEMBL8045859 | 0.80 | HDAC6 (0.51) | — | |
| SCHEMBL8044989 | 0.79 | SMN1; SMN2 (0.40) | BLMCYP2D6SLC22A2SLC22A1PGR | |
| SCHEMBL9450076 | 0.78 | CYP2D6 (0.45) | BLMCYP2D6SLC22A2SLC22A1PGR | |
| SCHEMBL8035702 | 0.78 | SMN1; SMN2 (0.40) | BLMCYP2D6SLC22A2SLC22A1PGR | |
| SCHEMBL11619910 | 0.78 | CYP2D6 (0.70) | BLMCYP2D6SLC22A2SLC22A1PGR | |
| SCHEMBL14921243 | 0.78 | CCR1 (0.47) | CYP2D6CCR1DRD2DRD4OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997024325-A1 | DIPHENYLMETHANE DERIVATIVES AS MIP-1α/RANTES RECEPTOR ANTAGONISTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-07-10 | — | — | WO | disclosed |