Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 2/20 | 0.39 |
| ▸ | CCR1 | P32246 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.39 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.39 |
| ▸ | TBXAS1 | P24557 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.38 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.38 |
| ▸ | PGR | P06401 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8044989 | 0.99 | SMN1; SMN2 (0.40) | SMN1; SMN2KCNA3OPRM1MEN1GAA | |
| SCHEMBL8891230 | 0.91 | SMN1; SMN2 (0.43) | SMN1; SMN2KCNA3OPRM1MEN1GAA | |
| SCHEMBL8044856 | 0.88 | OPRM1 (0.48) | SMN1; SMN2KCNA3OPRM1FAAHCCR1 | |
| SCHEMBL8049892 | 0.88 | OPRM1 (0.48) | SMN1; SMN2KCNA3OPRM1FAAHCCR1 | |
| SCHEMBL8046235 | 0.86 | OPRM1 (0.49) | SMN1; SMN2KCNA3OPRM1CCR1CYP4F2 | |
| SCHEMBL31585050 | 0.85 | SMN1; SMN2 (0.41) | SMN1; SMN2KCNA3OPRM1MEN1GAA | |
| SCHEMBL8052916 | 0.83 | HDAC6 (0.41) | CCR1HDAC6BLMCYP2D6SLC22A2 | |
| SCHEMBL7830375 | 0.83 | OPRM1 (0.50) | SMN1; SMN2KCNA3OPRM1CCR1CYP4F2 | |
| SCHEMBL8044839 | 0.82 | CYSLTR2 (0.45) | SMN1; SMN2KCNA3OPRM1MEN1KMT2A | |
| SCHEMBL8035219 | 0.82 | ALOX5 (0.39) | SMN1; SMN2KCNA3OPRM1FAAHCYP4F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0749957-B1 | Aromatic hydroxamic acid compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2000-04-26 | — | — | EP | disclosed |
| US-5891916-A | ANTINEUROGEGERATIVE AGENT | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1999-04-06 | — | — | US | disclosed |
| EP-0749957-A1 | Aromatic hydroxamic acid compounds, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1996-12-27 | — | — | EP | disclosed |