Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 2/20 | 0.36 |
| ▸ | CA12 | O43570 | 4/20 | 0.35 |
| ▸ | CA1 | P00915 | 4/20 | 0.35 |
| ▸ | CA2 | P00918 | 4/20 | 0.35 |
| ▸ | CA9 | Q16790 | 4/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 3/20 | 0.33 |
| ▸ | MAOA | P21397 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | GRK6 | P43250 | 1/20 | 0.32 |
| ▸ | CA6 | P23280 | 1/20 | 0.32 |
| ▸ | CA5A | P35218 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8891249 | 0.75 | TSHR (0.50) | KMT2ACA12CA1CA2CA9 | |
| SCHEMBL13969733 | 0.69 | KMT2A (0.66) | RECQLNPC1KMT2AGFERCA12 | |
| SCHEMBL2044233 | 0.69 | RECQL (0.67) | RECQLGFERCA12CA1CA2 | |
| SCHEMBL31028744 | 0.67 | CA2 (0.51) | CA12CA1CA2CA9HTT | |
| SCHEMBL11281060 | 0.66 | RECQL (0.69) | RECQLGFERCA12CA1CA2 | |
| SCHEMBL10765545 | 0.66 | RECQL (0.62) | RECQLGFERCA12CA1CA2 | |
| SCHEMBL6509990 | 0.65 | MAOB (0.57) | RECQLNPC1KMT2AGFERCA12 | |
| SCHEMBL11166463 | 0.65 | RECQL (0.96) | RECQLGFERCA12CA1CA2 | |
| SCHEMBL25230363 | 0.63 | CA12 (0.40) | CA12CA1CA2CA9 | |
| SCHEMBL8899345 | 0.63 | RECQL (0.64) | RECQLGFERCA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997024340-A1 | OXAZOLE DERIVATIVES, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-07-10 | — | — | WO | disclosed |