Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 5/20 | 0.63 |
| ▸ | CPB1 | P15086 | 1/20 | 0.58 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.58 |
| ▸ | TGM2 | P21980 | 4/20 | 0.56 |
| ▸ | MMP2 | P08253 | 2/20 | 0.55 |
| ▸ | MMP9 | P14780 | 2/20 | 0.55 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.55 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.55 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.52 |
| ▸ | ITGAV | P06756 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23113656 | 0.94 | FOLH1 (0.71) | FOLH1CPB1CPB2TGM2MMP2 | |
| SCHEMBL9389258 | 0.87 | FOLH1 (0.61) | FOLH1CPB1CPB2TGM2MMP2 | |
| SCHEMBL24130579 | 0.87 | FOLH1 (0.64) | FOLH1CPB1CPB2TGM2MMP2 | |
| SCHEMBL4539252 | 0.86 | FOLH1 (0.69) | FOLH1CPB1CPB2TGM2MMP2 | |
| SCHEMBL464715 | 0.86 | FOLH1 (0.78) | FOLH1CPB1CPB2TGM2MMP2 | |
| SCHEMBL4561005 | 0.86 | FOLH1 (0.78) | FOLH1CPB1CPB2TGM2MMP2 | |
| SCHEMBL806151 | 0.86 | FOLH1 (0.78) | FOLH1CPB1CPB2TGM2MMP2 | |
| SCHEMBL15976615 | 0.85 | CA1 (0.66) | FOLH1CPB1CPB2MMP2MMP9 | |
| SCHEMBL12247713 | 0.84 | FOLH1 (0.63) | FOLH1CPB1CPB2TGM2MMP2 | |
| SCHEMBL29072085 | 0.84 | FOLH1 (0.76) | FOLH1CPB1CPB2MMP2MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5599791-A | BACTERICIDE ACTIVE AGAINST GRAMNEGATIVE AND GRAMPOSITIVE BACTERIA | GRUPPO LEPETIT SPA (IT) | 1997-02-04 | — | — | US | disclosed |
| WO-1992012172-A9 | AMIDES OF ANTIBIOTIC GE 2270 FACTORS | — | 1996-04-04 | — | — | WO | disclosed |
| EP-0565567-A1 | AMIDES OF ANTIBIOTIC GE 2270 FACTORS. | LEPETIT SPA (IT) | 1993-10-20 | — | — | EP | disclosed |
| WO-1992012172-A1 | AMIDES OF ANTIBIOTIC GE 2270 FACTORS | GRUPPO LEPETIT S.P.A. (IT) | 1992-07-23 | — | — | WO | disclosed |
| EP-0494078-A1 | Amides of antibiotic ge 2270 factors | GRUPPO LEPETIT S.p.A. (IT) | 1992-07-08 | — | — | EP | disclosed |