Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 1/20 | 0.35 |
| ▸ | CDK2 | P24941 | 5/20 | 0.33 |
| ▸ | CCNE1 | P24864 | 4/20 | 0.32 |
| ▸ | GSK3B | P49841 | 4/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
| ▸ | JAK1 | P23458 | 1/20 | 0.32 |
| ▸ | TYK2 | P29597 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.30 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.30 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.30 |
| ▸ | DHODH | Q02127 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8889307 | 0.92 | NR3C1 (0.35) | NR3C1CDK2CCNE1GSK3BALDH1A1 | |
| SCHEMBL8890477 | 0.90 | NR3C1 (0.38) | NR3C1CDK2CCNE1GSK3BALDH1A1 | |
| SCHEMBL8890367 | 0.89 | NR3C1 (0.35) | NR3C1CDK2CCNE1GSK3BALDH1A1 | |
| SCHEMBL8890226 | 0.89 | NR3C1 (0.35) | NR3C1CDK2CCNE1GSK3BJAK2 | |
| SCHEMBL8890152 | 0.84 | LMNA (0.36) | NR3C1CDK2CCNE1GSK3BJAK2 | |
| SCHEMBL8890011 | 0.83 | PDE2A (0.31) | TAS1R3TAS1R1TAS1R2DHODH | |
| SCHEMBL8892156 | 0.83 | HPGD (0.36) | ALDH1A1LMNATAS1R3TAS1R1TAS1R2 | |
| SCHEMBL6054844 | 0.83 | DHODH (0.35) | ALDH1A1LMNAEPHX2TAS1R3TAS1R1 | |
| SCHEMBL6054845 | 0.83 | DHODH (0.33) | DHODH | |
| SCHEMBL8891637 | 0.82 | LMNA (0.34) | NR3C1CDK2CCNE1GSK3BALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997028136-A1 | BENZOYLISOXAZOLES AND 2-CYANO-1,3-DIONE DERIVATIVES AND THEIR USE AS HERBICIDES | RHONE-POULENC AGRICULTURE LTD. (GB) | 1997-08-07 | — | — | WO | disclosed |