Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 17/20 | 0.66 |
| ▸ | MTNR1B | P49286 | 11/20 | 0.66 |
| ▸ | HTR2B | P41595 | 2/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NQO2 | P16083 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.39 |
| ▸ | MPO | P05164 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8882996 | 0.88 | MTNR1A (0.56) | MTNR1AMTNR1BRAB9ANPC1KDM4E | |
| SCHEMBL8884153 | 0.88 | MTNR1A (0.57) | MTNR1AMTNR1BRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL8886559 | 0.85 | MTNR1A (0.69) | MTNR1AMTNR1BSMN1; SMN2KDM4E | |
| SCHEMBL8883211 | 0.84 | MTNR1A (0.54) | MTNR1AMTNR1BRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL8883208 | 0.82 | MTNR1A (0.51) | MTNR1AMTNR1BRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL8888429 | 0.82 | MTNR1A (0.51) | MTNR1AMTNR1BHTR2CKDM4EHPGD | |
| SCHEMBL8884003 | 0.82 | MTNR1A (0.56) | MTNR1AMTNR1BSMN1; SMN2 | |
| SCHEMBL8884185 | 0.80 | CYP2A6 (0.51) | MTNR1ASMN1; SMN2 | |
| SCHEMBL7024784 | 0.80 | MTNR1A (1.00) | MTNR1AMTNR1BHTR2BHTR2CRAB9A | |
| SCHEMBL8617176 | 0.79 | MTNR1A (0.54) | MTNR1AMTNR1BHTR2BRAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5612368-A | SKIN DISORDERS, MELATONINERGIC SYSTEMS, ANTIARRHYTHMIA AGENTS OR ANTIISCHEMIC AGENTS | ADIR ET COMPAGNIE (FR) | 1997-03-18 | — | — | US | disclosed |