Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 11/20 | 0.57 |
| ▸ | MTNR1B | P49286 | 5/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8892513 | 0.88 | MTNR1A (0.66) | MTNR1AMTNR1BSMN1; SMN2NPC1RAB9A | |
| SCHEMBL8883211 | 0.87 | MTNR1A (0.54) | MTNR1AMTNR1BSMN1; SMN2NPC1RAB9A | |
| SCHEMBL8883208 | 0.85 | MTNR1A (0.51) | MTNR1AMTNR1BSMN1; SMN2NPC1RAB9A | |
| SCHEMBL8888429 | 0.81 | MTNR1A (0.51) | MTNR1AMTNR1BKDM4EHPGD | |
| SCHEMBL8884785 | 0.79 | MTNR1A (0.55) | MTNR1AMTNR1BSMN1; SMN2 | |
| SCHEMBL8882996 | 0.78 | MTNR1A (0.56) | MTNR1AMTNR1BNPC1RAB9AKDM4E | |
| SCHEMBL8617176 | 0.77 | MTNR1A (0.54) | MTNR1AMTNR1BNPC1RAB9AKDM4E | |
| SCHEMBL28559146 | 0.77 | MTNR1A (0.61) | MTNR1AMTNR1B | |
| SCHEMBL8659213 | 0.77 | MTNR1A (0.84) | MTNR1AMTNR1B | |
| SCHEMBL8886559 | 0.76 | MTNR1A (0.69) | MTNR1AMTNR1BSMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5612368-A | SKIN DISORDERS, MELATONINERGIC SYSTEMS, ANTIARRHYTHMIA AGENTS OR ANTIISCHEMIC AGENTS | ADIR ET COMPAGNIE (FR) | 1997-03-18 | — | — | US | disclosed |