Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 5/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.38 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.38 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8891512 | 0.92 | HPGD (0.36) | HPGDALDH1A1RAB9ASMN1; SMN2CASP3 | |
| SCHEMBL8900763 | 0.92 | HPGD (0.38) | HPGDALDH1A1RAB9ASMN1; SMN2CASP3 | |
| SCHEMBL8889886 | 0.90 | HPGD (0.36) | HPGDALDH1A1RAB9ASMN1; SMN2CASP3 | |
| SCHEMBL8891465 | 0.90 | HPGD (0.39) | HPGDALDH1A1RAB9ASMN1; SMN2CASP3 | |
| SCHEMBL8892490 | 0.88 | HPGD (0.36) | HPGDALDH1A1RAB9ASMN1; SMN2CASP3 | |
| SCHEMBL8889689 | 0.83 | HPGD (0.39) | HPGDALDH1A1RAB9ASMN1; SMN2CASP3 | |
| SCHEMBL8889692 | 0.83 | ALDH1A1 (0.37) | HPGDALDH1A1RAB9ASMN1; SMN2CASP3 | |
| SCHEMBL8890370 | 0.83 | HPGD (0.34) | HPGDALDH1A1RAB9ASMN1; SMN2CASP3 | |
| SCHEMBL8907895 | 0.82 | HPGD (0.36) | HPGDALDH1A1RAB9ASMN1; SMN2CASP3 | |
| SCHEMBL8892156 | 0.82 | HPGD (0.36) | HPGDALDH1A1RAB9ASMN1; SMN2CASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997028136-A1 | BENZOYLISOXAZOLES AND 2-CYANO-1,3-DIONE DERIVATIVES AND THEIR USE AS HERBICIDES | RHONE-POULENC AGRICULTURE LTD. (GB) | 1997-08-07 | — | — | WO | disclosed |