Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.36 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.36 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8892156 | 0.92 | HPGD (0.36) | HPGDSMN1; SMN2ALDH1A1CASP3RAB9A | |
| SCHEMBL8891465 | 0.90 | HPGD (0.39) | HPGDSMN1; SMN2ALDH1A1CASP3RAB9A | |
| SCHEMBL8892579 | 0.88 | HPGD (0.38) | HPGDSMN1; SMN2ALDH1A1CASP3RAB9A | |
| SCHEMBL8891280 | 0.83 | CYP19A1 (0.33) | CYP19A1TAS1R3TAS1R1TAS1R2GSTA1 | |
| SCHEMBL8889307 | 0.83 | NR3C1 (0.35) | ALDH1A1CYP19A1LMNATAS1R3TAS1R1 | |
| SCHEMBL8889689 | 0.83 | HPGD (0.39) | HPGDSMN1; SMN2ALDH1A1CASP3RAB9A | |
| SCHEMBL8889692 | 0.83 | ALDH1A1 (0.37) | HPGDSMN1; SMN2ALDH1A1CASP3RAB9A | |
| SCHEMBL8890370 | 0.83 | HPGD (0.34) | HPGDSMN1; SMN2ALDH1A1CASP3RAB9A | |
| SCHEMBL8890982 | 0.82 | LMNA (0.34) | HPGDSMN1; SMN2ALDH1A1CASP3RAB9A | |
| SCHEMBL8891512 | 0.82 | HPGD (0.36) | HPGDSMN1; SMN2ALDH1A1CASP3RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997028136-A1 | BENZOYLISOXAZOLES AND 2-CYANO-1,3-DIONE DERIVATIVES AND THEIR USE AS HERBICIDES | RHONE-POULENC AGRICULTURE LTD. (GB) | 1997-08-07 | — | — | WO | disclosed |