Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 3/20 | 0.40 |
| ▸ | F11 | P03951 | 5/20 | 0.40 |
| ▸ | KLKB1 | P03952 | 5/20 | 0.40 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.38 |
| ▸ | AR | P10275 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.38 |
| ▸ | PLG | P00747 | 1/20 | 0.38 |
| ▸ | PLAT | P00750 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL8892655 | 0.82 | NPC1 (0.40) | AGTR2ARFFAR1NPC1RAB9A | |
| Trifluoroacetic Acid SCHEMBL9023400 | 0.78 | SLC6A2 (0.41) | CHRM3CRBNKMT2A | |
| SCHEMBL2665515 | 0.78 | ALDH1A1 (0.50) | AGTR2ARFFAR1NPC1RAB9A | |
| SCHEMBL8892650 | 0.73 | AR (0.36) | AGTR2ARFFAR1NPC1RAB9A | |
| Trifluoroacetic Acid SCHEMBL8916303 | 0.73 | PLG (0.42) | CHRM3F11KLKB1PLGPLAT | |
| Trifluoroacetic Acid SCHEMBL8901689 | 0.73 | PLG (0.42) | CHRM3F11KLKB1PLGPLAT | |
| SCHEMBL15477388 | 0.70 | SMN1; SMN2 (0.48) | AGTR2FFAR1NPC1RAB9A | |
| SCHEMBL17040211 | 0.70 | NPC1 (0.43) | AGTR2ARNPC1RAB9ACRBN | |
| SCHEMBL9023404 | 0.69 | AGTR2 (0.40) | AGTR2NPC1RAB9A | |
| SCHEMBL5548726 | 0.67 | AGTR2 (0.41) | AGTR2FFAR1NPC1RAB9ACRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997020823-A2 | 2-AMINO QUINAZOLINE DERIVATIVES AS NPY RECEPTOR ANTAGONISTS | NOVARTIS AG (CH) | 1997-06-12 | — | — | WO | disclosed |