SCHEMBL8892668

SCHEMBL8892668

O=S(=O)(O)c1cc(S(=O)(=O)O)c2cccc(S(=O)(=O)O)c2c1.[NaH].[NaH].[NaH].[NaH].[NaH].[NaH]

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TTR P02766 1/20 0.55
ATIC P31939 3/20 0.47
SUMO2 P61956 2/20 0.47
SUMO1 P63165 2/20 0.47
SENP7 Q9BQF6 2/20 0.47
SENP2 Q9HC62 2/20 0.47
CYP1A2 P05177 2/20 0.43
ALDH1A1 P00352 4/20 0.42
HSD17B10 Q99714 3/20 0.42
CYP2C9 P11712 1/20 0.42
CYP2C19 P33261 1/20 0.42
CASP6 P55212 1/20 0.42
MPL P40238 3/20 0.41
TDP1 Q9NUW8 3/20 0.41
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
USP2 O75604 1/20 0.41
TIMP3 P35625 1/20 0.41
RECQL P46063 1/20 0.41
TSHR P16473 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6380343 1.00 TTR (0.55) TTRATICSUMO2SUMO1SENP7
SCHEMBL6556646 1.00 TTR (0.55) TTRATICSUMO2SUMO1SENP7
SCHEMBL3032086 0.98 TTR (0.56) TTRATICSUMO2SUMO1SENP7
SCHEMBL7162743 0.98 TTR (0.56) TTRATICSUMO2SUMO1SENP7
SCHEMBL31151117 0.98 TTR (0.56) TTRATICSUMO2SUMO1SENP7
SCHEMBL6385053 0.96 TTR (0.55) TTRATICSUMO2SUMO1SENP7
SCHEMBL3816121 0.86 ALDH1A1 (0.47) ALDH1A1HSD17B10CYP2C9CYP2C19CASP6
SCHEMBL27502670 0.86 NSD2 (0.49) TTRATICCYP1A2ALDH1A1HSD17B10
SCHEMBL8028660 0.84 TTR (0.72) TTRATICSUMO2SUMO1SENP7
SCHEMBL3899723 0.84 ALDH1A1 (0.48) ALDH1A1HSD17B10CYP2C9CYP2C19CASP6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5593976-A New ureido derivatives of poly-4-amino-2-carboxy-1-methyl compounds FARMITALIA CARLO ERBA S R L (IT) 1997-01-14 US disclosed
EP-0462258-B1 UREIDO DERIVATIVES OF POLY-4-AMINO-2-CARBOXY-1-METHYL COMPOUNDS PHARMACIA SPA (IT) 1995-12-20 EP disclosed
EP-0462258-A1 NEW UREIDO DERIVATIVES OF POLY-4-AMINO-2-CARBOXY-1-METHYL COMPOUNDS. ERBA CARLO SPA (IT) 1991-12-27 EP disclosed
WO-1991010649-A1 NEW UREIDO DERIVATIVES OF POLY-4-AMINO-2-CARBOXY-1-METHYL COMPOUNDS FARMITALIA CARLO ERBA S.R.L. (IT) 1991-07-25 WO disclosed