Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 1/20 | 0.55 |
| ▸ | ATIC | P31939 | 3/20 | 0.47 |
| ▸ | SUMO2 | P61956 | 2/20 | 0.47 |
| ▸ | SUMO1 | P63165 | 2/20 | 0.47 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.47 |
| ▸ | SENP2 | Q9HC62 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | CASP6 | P55212 | 1/20 | 0.42 |
| ▸ | MPL | P40238 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | TIMP3 | P35625 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6556646 | 1.00 | TTR (0.55) | TTRATICSUMO2SUMO1SENP7 | |
| SCHEMBL8892668 | 1.00 | TTR (0.55) | TTRATICSUMO2SUMO1SENP7 | |
| SCHEMBL3032086 | 0.98 | TTR (0.56) | TTRATICSUMO2SUMO1SENP7 | |
| SCHEMBL7162743 | 0.98 | TTR (0.56) | TTRATICSUMO2SUMO1SENP7 | |
| SCHEMBL31151117 | 0.98 | TTR (0.56) | TTRATICSUMO2SUMO1SENP7 | |
| SCHEMBL6385053 | 0.96 | TTR (0.55) | TTRATICSUMO2SUMO1SENP7 | |
| SCHEMBL3816121 | 0.86 | ALDH1A1 (0.47) | ALDH1A1HSD17B10CYP2C9CYP2C19CASP6 | |
| SCHEMBL27502670 | 0.86 | NSD2 (0.49) | TTRATICCYP1A2ALDH1A1HSD17B10 | |
| SCHEMBL8028660 | 0.84 | TTR (0.72) | TTRATICSUMO2SUMO1SENP7 | |
| SCHEMBL3899723 | 0.84 | ALDH1A1 (0.48) | ALDH1A1HSD17B10CYP2C9CYP2C19CASP6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050222455-A1 | Method for producing 3-hydroxy-2-methylbenzoic acid | BAYER CHEMICALS AG (DE) | 2005-10-06 | — | — | US | claimed |
| US-6891060-B2 | Preparation of 3-acyloxy-2-methylbenzoic acids | BAYERAKTIENGESELLSCHAFT (DE) | 2005-05-10 | — | — | US | claimed |
| US-20040044243-A1 | Preparation of 3-acyloxy-2-methylbenzoic acids | LANXESS DEUTSCHLAND GMBH (DE) | 2004-03-04 | — | — | US | claimed |
| US-20180048011-A1 | HIGH pH ORGANIC FLOW BATTERY | U.S. DEPARTMENT OF ENERGY | 2018-02-15 | — | — | US | disclosed |
| US-20050222455-A1 | Method for producing 3-hydroxy-2-methylbenzoic acid | BAYER CHEMICALS AG (DE) | 2005-10-06 | — | — | US | disclosed |
| CN-1642895-A | Method for producing 3-hydroxy-2-methylbenzoic acid | BAYER AG (DE) | 2005-07-20 | — | — | CN | disclosed |
| US-6891060-B2 | Preparation of 3-acyloxy-2-methylbenzoic acids | BAYERAKTIENGESELLSCHAFT (DE) | 2005-05-10 | — | — | US | disclosed |
| US-20040260119-A1 | Preparation of 3-alkoxy-2-methylbenzoic acids | LANXESS DEUTSCHLAND GMBH (DE) | 2004-12-23 | — | — | US | disclosed |
| US-20040044243-A1 | Preparation of 3-acyloxy-2-methylbenzoic acids | LANXESS DEUTSCHLAND GMBH (DE) | 2004-03-04 | — | — | US | disclosed |
| US-6562859-B1 | A method of inhibiting the onset of non-TNF- alpha dependent inflammation, which comprises administering to a mammal exposed to an inflammation-causing condition or disease an inflammation- inhibiting effective amount of a compound of the | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES | 2003-05-13 | — | — | US | disclosed |
| WO-1999027939-A1 | UREIDO DERIVATIVES OF POLY-4-AMINO-2-CARBOXY-1-METHYL PYRROLE COMPOUNDS FOR INHIBITION OF INFLAMMATION | THE GOVERNMENT OF THE UNITED STATES OF AMERICA, REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 1999-06-10 | — | — | WO | disclosed |
| US-5593976-A | New ureido derivatives of poly-4-amino-2-carboxy-1-methyl compounds | FARMITALIA CARLO ERBA S R L (IT) | 1997-01-14 | — | — | US | disclosed |
| EP-0462258-B1 | UREIDO DERIVATIVES OF POLY-4-AMINO-2-CARBOXY-1-METHYL COMPOUNDS | PHARMACIA SPA (IT) | 1995-12-20 | — | — | EP | disclosed |
| US-5420296-A | Ureido derivatives of poly-4-amino-2-carboxy-1-methyl compounds | FARMITALIA CARLO ERBA S R L (IT) | 1995-05-30 | — | — | US | disclosed |
| US-5260329-A | Ureido derivatives of poly-4-amino-2-carboxy-1-methyl compounds | FARMITALIA CARLO ERBA SRL (IT) | 1993-11-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040260119-A1 | Preparation of 3-alkoxy-2-methylbenzoic acids | TET2, ALKBH2, ALKBH3 | TTR 2201/4885ATIC 1165/4885SUMO2 2300/4885 |
| US-20040044243-A1 | Preparation of 3-acyloxy-2-methylbenzoic acids | TET2, NAAA, APEH | TTR 2553/4885ATIC 1491/4885SUMO2 2450/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.