Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A3 | P43003 | 1/20 | 0.49 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.49 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.49 |
| ▸ | METAP2 | P50579 | 1/20 | 0.48 |
| ▸ | F2 | P00734 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | ANPEP | P15144 | 3/20 | 0.43 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.43 |
| ▸ | DNPEP | Q9ULA0 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.41 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.41 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.40 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 2/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8892685 | 1.00 | SLC1A3 (0.49) | SLC1A3SLC1A2SLC1A1METAP2F2 | |
| SCHEMBL8894259 | 0.88 | LDHA (0.54) | SLC1A3SLC1A2SLC1A1F2CYP1A2 | |
| SCHEMBL8894272 | 0.88 | LDHA (0.54) | SLC1A3SLC1A2SLC1A1F2CYP1A2 | |
| SCHEMBL8895932 | 0.84 | SLC1A3 (0.44) | SLC1A3SLC1A2SLC1A1METAP2F2 | |
| SCHEMBL8895937 | 0.84 | SLC1A3 (0.44) | SLC1A3SLC1A2SLC1A1METAP2F2 | |
| SCHEMBL7436311 | 0.83 | SLC1A3 (0.68) | SLC1A3SLC1A2SLC1A1CYP1A2ANPEP | |
| SCHEMBL7436306 | 0.83 | SLC1A3 (0.68) | SLC1A3SLC1A2SLC1A1CYP1A2ANPEP | |
| SCHEMBL8894736 | 0.83 | SLC1A3 (0.48) | SLC1A3SLC1A2SLC1A1F2CYP1A2 | |
| SCHEMBL8894728 | 0.83 | SLC1A3 (0.48) | SLC1A3SLC1A2SLC1A1F2CYP1A2 | |
| SCHEMBL8893679 | 0.83 | SLC1A3 (0.54) | SLC1A3SLC1A2SLC1A1CYP1A2ANPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5643878-A | TREATMENT OF RETROVIRAL DISEASES LIKE AIDS | CIBA-GEIGY CORPORATION (US) | 1997-07-01 | — | — | US | disclosed |