Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A3 | P43003 | 1/20 | 0.48 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.48 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | PPARA | Q07869 | 2/20 | 0.44 |
| ▸ | F2 | P00734 | 1/20 | 0.44 |
| ▸ | BCHE | P06276 | 3/20 | 0.44 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.43 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.43 |
| ▸ | BACE1 | P56817 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.42 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.42 |
| ▸ | GRIK3 | Q13003 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8894736 | 1.00 | SLC1A3 (0.48) | SLC1A3SLC1A2SLC1A1ALDH1A1GAA | |
| SCHEMBL8895907 | 0.93 | CYP1A2 (0.50) | SLC1A3SLC1A2SLC1A1ALDH1A1GAA | |
| SCHEMBL8895912 | 0.93 | CYP1A2 (0.50) | SLC1A3SLC1A2SLC1A1ALDH1A1GAA | |
| SCHEMBL8895937 | 0.86 | SLC1A3 (0.44) | SLC1A3SLC1A2SLC1A1ALDH1A1CYP1A2 | |
| SCHEMBL8895932 | 0.86 | SLC1A3 (0.44) | SLC1A3SLC1A2SLC1A1ALDH1A1CYP1A2 | |
| SCHEMBL8894272 | 0.83 | LDHA (0.54) | SLC1A3SLC1A2SLC1A1CYP1A2PPARA | |
| SCHEMBL8892676 | 0.83 | SLC1A3 (0.49) | SLC1A3SLC1A2SLC1A1ALDH1A1CYP1A2 | |
| SCHEMBL8892685 | 0.83 | SLC1A3 (0.49) | SLC1A3SLC1A2SLC1A1ALDH1A1CYP1A2 | |
| SCHEMBL8894259 | 0.83 | LDHA (0.54) | SLC1A3SLC1A2SLC1A1CYP1A2PPARA | |
| SCHEMBL7436311 | 0.83 | SLC1A3 (0.68) | SLC1A3SLC1A2SLC1A1CYP1A2ANPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5643878-A | TREATMENT OF RETROVIRAL DISEASES LIKE AIDS | CIBA-GEIGY CORPORATION (US) | 1997-07-01 | — | — | US | disclosed |
| EP-0618222-A2 | Dipeptid derivatives of 5-amino-4-hydroxy-hexanoic acid | CIBA-GEIGY AG (CH) | 1994-10-05 | — | — | EP | disclosed |