Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | METAP2 | P50579 | 1/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.35 |
| ▸ | PIEZO1 | Q92508 | 2/20 | 0.35 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.34 |
| ▸ | TERT | O14746 | 4/20 | 0.34 |
| ▸ | GRM5 | P41594 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20169526 | 0.82 | NPC1 (0.44) | NPC1RAB9APKMKDM4EGLA | |
| SCHEMBL4780009 | 0.79 | NPC1 (0.46) | NPC1RAB9APKMKDM4EGLA | |
| SCHEMBL29086411 | 0.77 | NPC1 (0.47) | NPC1RAB9APKMKDM4EGLA | |
| SCHEMBL30620644 | 0.77 | NPC1 (0.47) | NPC1RAB9APKMKDM4EGLA | |
| SCHEMBL27877202 | 0.77 | NPC1 (0.41) | NPC1RAB9APKMKDM4EGLA | |
| SCHEMBL8363958 | 0.77 | KDM4E (0.42) | NPC1RAB9APKMKDM4EGLA | |
| SCHEMBL27877133 | 0.77 | KDM4E (0.45) | NPC1RAB9APKMKDM4EGLA | |
| SCHEMBL8891318 | 0.74 | KDM4E (0.65) | NPC1RAB9APKMKDM4EGRM5 | |
| SCHEMBL22147393 | 0.74 | NPC1 (0.54) | NPC1RAB9APKMKDM4EMETAP2 | |
| SCHEMBL17486063 | 0.74 | RAB9A (0.49) | NPC1RAB9APKMKDM4EMETAP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5626791-A | FERROELECTRIC LIQUID CRYSTALS | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-05-06 | — | — | US | disclosed |