Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NMBR | P28336 | 12/20 | 0.53 |
| ▸ | GRPR | P30550 | 11/20 | 0.52 |
| ▸ | FPR2 | P25090 | 1/20 | 0.44 |
| ▸ | CCKBR | P32239 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8892713 | 1.00 | NMBR (0.53) | NMBRGRPRFPR2CCKBR | |
| SCHEMBL8901324 | 0.91 | NMBR (0.55) | NMBRGRPRCCKBR | |
| SCHEMBL8901328 | 0.91 | NMBR (0.55) | NMBRGRPRCCKBR | |
| SCHEMBL28360002 | 0.80 | TACR1 (0.49) | NMBRCCKBR | |
| SCHEMBL30060549 | 0.80 | TACR1 (0.49) | NMBRCCKBR | |
| SCHEMBL9085407 | 0.78 | NMBR (0.72) | NMBRGRPR | |
| SCHEMBL8699599 | 0.77 | KMT2A (0.63) | FPR2 | |
| SCHEMBL9377089 | 0.77 | NMBR (0.61) | NMBRGRPRCCKBR | |
| SCHEMBL15145375 | 0.74 | NMBR (0.48) | NMBRCCKBR | |
| SCHEMBL14595065 | 0.72 | KDM4E (0.55) | NMBR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5593967-A | Cholecystokinin antagonists, their preparation and therapeutic use | WARNER-LAMBERT COMPANY (US) | 1997-01-14 | — | — | US | disclosed |
| WO-1992004045-A1 | NOVEL CHOLECYSTOKININ ANTAGONISTS, THEIR PREPARATION AND THERAPEUTIC USE | WARNER-LAMBERT COMPANY (US) | 1992-03-19 | — | — | WO | disclosed |