Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NMBR | P28336 | 17/20 | 0.55 |
| ▸ | GRPR | P30550 | 15/20 | 0.54 |
| ▸ | CCKBR | P32239 | 1/20 | 0.44 |
| ▸ | FPR1 | P21462 | 1/20 | 0.43 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.43 |
| ▸ | GPR65 | Q8IYL9 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8901324 | 1.00 | NMBR (0.55) | NMBRGRPRCCKBRFPR1AGTR1 | |
| SCHEMBL8892719 | 0.91 | NMBR (0.53) | NMBRGRPRCCKBR | |
| SCHEMBL8892713 | 0.91 | NMBR (0.53) | NMBRGRPRCCKBR | |
| SCHEMBL6306355 | 0.81 | CCKBR (0.51) | NMBRCCKBR | |
| SCHEMBL6306358 | 0.81 | CCKBR (0.51) | NMBRCCKBR | |
| SCHEMBL9085407 | 0.80 | NMBR (0.72) | NMBRGRPRFPR1AGTR1GPR65 | |
| SCHEMBL9377089 | 0.79 | NMBR (0.61) | NMBRGRPRCCKBR | |
| SCHEMBL22835926 | 0.75 | NMBR (0.53) | NMBRCCKBR | |
| SCHEMBL8699599 | 0.75 | KMT2A (0.63) | FPR1 | |
| SCHEMBL6339800 | 0.74 | MAPT (0.52) | NMBRCCKBR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5593967-A | Cholecystokinin antagonists, their preparation and therapeutic use | WARNER-LAMBERT COMPANY (US) | 1997-01-14 | — | — | US | disclosed |
| WO-1992004045-A1 | NOVEL CHOLECYSTOKININ ANTAGONISTS, THEIR PREPARATION AND THERAPEUTIC USE | WARNER-LAMBERT COMPANY (US) | 1992-03-19 | — | — | WO | disclosed |