Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.56 |
| ▸ | USP2 | O75604 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | GPR119 | Q8TDV5 | 9/20 | 0.49 |
| ▸ | FAAH | O00519 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6157453 | 0.91 | USP2 (0.60) | RECQLUSP2SMN1; SMN2GPR119FAAH | |
| SCHEMBL16293179 | 0.85 | RECQL (0.54) | RECQLUSP2SMN1; SMN2GPR119FAAH | |
| SCHEMBL30019783 | 0.85 | GPR119 (0.49) | GPR119FAAHPKM | |
| SCHEMBL27120931 | 0.85 | GPR119 (0.49) | GPR119FAAHPKM | |
| SCHEMBL1088712 | 0.84 | USP2 (0.62) | RECQLUSP2SMN1; SMN2GPR119FAAH | |
| SCHEMBL15352401 | 0.84 | SMN1; SMN2 (0.66) | RECQLUSP2SMN1; SMN2 | |
| SCHEMBL15353080 | 0.82 | SMN1; SMN2 (0.72) | RECQLUSP2SMN1; SMN2THRBALDH1A1 | |
| SCHEMBL15085741 | 0.82 | GPR119 (0.59) | RECQLUSP2SMN1; SMN2GPR119FAAH | |
| SCHEMBL27035708 | 0.82 | GPR119 (0.49) | GPR119FAAHPKM | |
| SCHEMBL3020153 | 0.81 | RECQL (0.58) | RECQLUSP2SMN1; SMN2THRBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997043292-A1 | NEW THIAZOLOPYRIDINES | KLINGE PHARMA GMBH (DE) | 1997-11-20 | — | — | WO | disclosed |