Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 11/20 | 0.49 |
| ▸ | FAAH | O00519 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8892846 | 0.85 | RECQL (0.56) | GPR119FAAHPKM | |
| SCHEMBL27120931 | 0.85 | GPR119 (0.49) | GPR119FAAHKDM4EPKMHPGD | |
| SCHEMBL4469087 | 0.84 | KDM4E (0.49) | GPR119FAAHKDM4EPKMCHRM2 | |
| SCHEMBL27140680 | 0.82 | SMN1; SMN2 (0.52) | GPR119FAAHKDM4EPKM | |
| SCHEMBL15085741 | 0.82 | GPR119 (0.59) | GPR119FAAHKDM4EPKMHPGD | |
| SCHEMBL8253901 | 0.82 | USP2 (0.51) | CHRM2CHRM1 | |
| SCHEMBL27035708 | 0.82 | GPR119 (0.49) | GPR119FAAHKDM4EPKMHPGD | |
| SCHEMBL29201747 | 0.82 | TPSAB1 (0.49) | GPR119FAAHCHRM2CHRM1HPGD | |
| SCHEMBL27120122 | 0.81 | HPGD (0.62) | GPR119FAAHCHRM2CHRM1HPGD | |
| SCHEMBL20873847 | 0.80 | USP2 (0.53) | CHRM2CHRM1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022223033-A1 | SOS1 DEGRADING AGENT AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 上海领泰生物医药科技有限公司 | 2022-10-27 | — | — | WO | disclosed |