Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 17/20 | 0.48 |
| ▸ | PSMB1 | P20618 | 2/20 | 0.46 |
| ▸ | PSMB8 | P28062 | 2/20 | 0.46 |
| ▸ | PSMB9 | P28065 | 2/20 | 0.46 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.46 |
| ▸ | PSMB10 | P40306 | 1/20 | 0.46 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.46 |
| ▸ | YAP1 | P46937 | 1/20 | 0.46 |
| ▸ | CTSD | P07339 | 1/20 | 0.44 |
| ▸ | PGA5 | P0DJD9 | 1/20 | 0.44 |
| ▸ | CTSE | P14091 | 1/20 | 0.44 |
| ▸ | PGC | P20142 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8892424 | 0.94 | REN (0.49) | RENCTSDPGA5CTSEPGC | |
| SCHEMBL8892017 | 0.94 | REN (0.51) | RENCTSDPGA5CTSEPGC | |
| SCHEMBL8891461 | 0.91 | PSMB1 (0.44) | RENPSMB1PSMB8PSMB9PSMB5 | |
| SCHEMBL1006593 | 0.86 | PSEN1 (0.54) | REN | |
| SCHEMBL8893248 | 0.86 | PSEN1 (0.54) | REN | |
| SCHEMBL8892662 | 0.85 | REN (0.42) | RENPSMB8PSMB9PSMB5PSMB10 | |
| SCHEMBL8892093 | 0.85 | REN (0.42) | REN | |
| SCHEMBL8893525 | 0.84 | REN (0.42) | RENPSMB1PSMB8PSMB9PSMB5 | |
| SCHEMBL8895266 | 0.84 | REN (0.42) | RENPSMB1PSMB8PSMB9PSMB5 | |
| SCHEMBL8896021 | 0.84 | REN (0.42) | RENPSMB1PSMB8PSMB9PSMB5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5643878-A | TREATMENT OF RETROVIRAL DISEASES LIKE AIDS | CIBA-GEIGY CORPORATION (US) | 1997-07-01 | — | — | US | disclosed |
| EP-0618222-A2 | Dipeptid derivatives of 5-amino-4-hydroxy-hexanoic acid | CIBA-GEIGY AG (CH) | 1994-10-05 | — | — | EP | disclosed |