Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 5/20 | 0.64 |
| ▸ | LAP3 | P28838 | 1/20 | 0.64 |
| ▸ | REN | P00797 | 1/20 | 0.60 |
| ▸ | PPARG | P37231 | 3/20 | 0.54 |
| ▸ | PPARA | Q07869 | 3/20 | 0.54 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.52 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.52 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.52 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.50 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.50 |
| ▸ | PPARD | Q03181 | 1/20 | 0.49 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 2/20 | 0.47 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.47 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.47 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.47 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8892764 | 1.00 | LTA4H (0.64) | LTA4HLAP3RENPPARGPPARA | |
| SCHEMBL8892768 | 1.00 | LTA4H (0.64) | LTA4HLAP3RENPPARGPPARA | |
| SCHEMBL8892421 | 1.00 | LTA4H (0.64) | LTA4HLAP3RENPPARGPPARA | |
| SCHEMBL8892426 | 1.00 | LTA4H (0.64) | LTA4HLAP3RENPPARGPPARA | |
| SCHEMBL8892873 | 1.00 | LTA4H (0.64) | LTA4HLAP3RENPPARGPPARA | |
| SCHEMBL8893453 | 0.94 | LTA4H (0.61) | LTA4HLAP3RENPPARGPPARA | |
| SCHEMBL8893456 | 0.94 | LTA4H (0.61) | LTA4HLAP3RENPPARGPPARA | |
| SCHEMBL8894863 | 0.87 | REN (0.52) | LTA4HLAP3RENSLC1A3SLC1A2 | |
| SCHEMBL8894868 | 0.87 | REN (0.52) | LTA4HLAP3RENSLC1A3SLC1A2 | |
| SCHEMBL7436311 | 0.87 | SLC1A3 (0.68) | LAP3SLC1A3SLC1A2SLC1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5643878-A | TREATMENT OF RETROVIRAL DISEASES LIKE AIDS | CIBA-GEIGY CORPORATION (US) | 1997-07-01 | — | — | US | disclosed |
| EP-0618222-A2 | Dipeptid derivatives of 5-amino-4-hydroxy-hexanoic acid | CIBA-GEIGY AG (CH) | 1994-10-05 | — | — | EP | disclosed |