Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMS | P04818 | 2/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | MAPT | P10636 | 3/20 | 0.59 |
| ▸ | POLB | P06746 | 2/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.59 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.59 |
| ▸ | FEN1 | P39748 | 1/20 | 0.59 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | BRD1 | O95696 | 1/20 | 0.42 |
| ▸ | TAF1 | P21675 | 1/20 | 0.42 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3437810 | 0.82 | TYMS (0.71) | TYMSKDM4ECYP1A2ALDH1A1MAPT | |
| SCHEMBL212889 | 0.78 | TYMS (1.00) | TYMSKDM4ECYP1A2ALDH1A1MAPT | |
| SCHEMBL29478287 | 0.78 | TYMS (1.00) | TYMSKDM4ECYP1A2ALDH1A1MAPT | |
| SCHEMBL7741124 | 0.78 | TYMS (0.67) | TYMSKDM4ECYP1A2ALDH1A1MAPT | |
| SCHEMBL29486055 | 0.78 | TYMS (1.00) | TYMSKDM4ECYP1A2ALDH1A1MAPT | |
| SCHEMBL31266544 | 0.77 | TYMS (0.64) | TYMSKDM4ECYP1A2ALDH1A1MAPT | |
| SCHEMBL10490163 | 0.77 | TYMS (0.64) | TYMSKDM4ECYP1A2ALDH1A1MAPT | |
| SCHEMBL11674314 | 0.77 | TYMS (0.65) | TYMSKDM4ECYP1A2ALDH1A1MAPT | |
| SCHEMBL5746127 | 0.77 | TYMS (0.65) | TYMSKDM4ECYP1A2ALDH1A1MAPT | |
| SCHEMBL9357590 | 0.77 | MAPT (0.50) | TYMSKDM4ECYP1A2ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997027179-A2 | ANTIRETROVIRAL BASES | NOVARTIS AG (CH) | 1997-07-31 | — | — | WO | disclosed |