SCHEMBL212889

SCHEMBL212889

O=C1OC(=O)c2ccc(Cl)c3cccc1c23

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TYMS P04818 5/20 1.00
KDM4E B2RXH2 3/20 0.61
ALDH1A1 P00352 3/20 0.61
TDP1 Q9NUW8 2/20 0.61
POLB P06746 2/20 0.61
CYP1A2 P05177 1/20 0.61
ERCC1 P07992 1/20 0.61
MAPT P10636 1/20 0.61
TSHR P16473 1/20 0.61
ALOX12 P18054 1/20 0.61
FEN1 P39748 1/20 0.61
ERCC4 Q92889 1/20 0.61
HPGD P15428 1/20 0.61
LMNA P02545 1/20 0.56
KMT2A Q03164 3/20 0.47
MEN1 O00255 2/20 0.46
L3MBTL1 Q9Y468 1/20 0.45
ALOX15 P16050 1/20 0.44
BRD1 O95696 1/20 0.43
TAF1 P21675 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29478287 1.00 TYMS (1.00) TYMSKDM4EALDH1A1TDP1POLB
SCHEMBL29486055 1.00 TYMS (1.00) TYMSKDM4EALDH1A1TDP1POLB
SCHEMBL3437810 0.83 TYMS (0.71) TYMSKDM4EALDH1A1TDP1POLB
SCHEMBL10267341 0.83 TYMS (0.70) TYMSKDM4EALDH1A1TDP1POLB
SCHEMBL7741124 0.80 TYMS (0.67) TYMSKDM4EALDH1A1TDP1POLB
SCHEMBL7709794 0.79 TYMS (0.66) TYMSKDM4EALDH1A1TDP1POLB
SCHEMBL8321557 0.79 TYMS (0.62) TYMSKDM4EALDH1A1TDP1POLB
SCHEMBL10490163 0.79 TYMS (0.64) TYMSKDM4EALDH1A1TDP1POLB
SCHEMBL11423048 0.79 TYMS (0.64) TYMSKDM4EALDH1A1TDP1POLB
SCHEMBL31266544 0.79 TYMS (0.64) TYMSKDM4EALDH1A1TDP1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1019 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118255796-A Tool molecule for exploring targeting property of BPA boron-like drug in tumor tissue and method for detecting distribution of BPA boron-like drug in tumor tissue 兰州大学 2024-06-28 CN claimed
CN-117820228-A Fluorescent probe for detecting L-tyrosine (L-Tyr), preparation method thereof and detection method 海南大学 2024-04-05 CN claimed
CN-113354618-B Hypochlorous acid fluorescent probe capable of targeting cell lysosome, preparation method and application 济南大学 2022-12-20 CN claimed
CN-114716600-A Synthesis and application of fluorescent polymer 上海未来企业股份有限公司 2022-07-08 CN claimed
CN-110198967-B Polyarylene ether sulfones with naphthalic anhydride end groups 巴斯夫欧洲公司 2022-04-05 CN claimed
US-11193020-B2 Polyarylene ether sulfone comprising naphthalic acid anhydride endgroups BASF SE (DE) 2021-12-07 US claimed
CN-111808097-B Solvent yellow 184 derivative and preparation method and application thereof 厦门大学 2021-10-22 CN claimed
EP-3577164-B1 POLYARYLENE ETHER SULFONE COMPRISING NAPHTHALIC ACID ANHYDRIDE ENDGROUPS BASF SE (DE) 2021-06-02 EP claimed
CN-111808097-A Solvent yellow 184 derivative and preparation method and application thereof 厦门大学 2020-10-23 CN claimed
CN-111155307-A Fluorescent hydrogel graft modified fabric and preparation method and application thereof 中国科学院宁波材料技术与工程研究所 2020-05-15 CN claimed
US-20040215038-A1 Colorant precursor compositions XEROX CORPORATION 2004-10-28 US claimed
US-20040215002-A1 Colorant compositions XEROX CORPORATION 2004-10-28 US claimed
US-20040215022-A1 Colorant compositions XEROX CORPORATION 2004-10-28 US claimed
US-6790267-B1 METHINE COLORANT COMPOUNDS FOR PHASE CHANGE INKS XEROX CORPORATION 2004-09-14 US claimed
US-6764541-B1 Colorant compositions XEROX CORPORATION 2004-07-20 US claimed
US-6251302-B1 FLUORESCENT DYES WITH POLYALKOXY GLYCOLS WITH 4-AMINO 1,8-NAPHTHALIMIDE MICROBIOMED CORPORATION 2001-06-26 US claimed
EP-0937752-A2 Naphthalimide colorants with improved compatibility in refrigeration and air conditioning lubricants MILLIKEN RESEARCH CORPORATION (US) 1999-08-25 EP claimed
US-5918269-A LEAK DETECTION COLORANTS IN REFRIGERATION AND AIR CONDITIONING SYSTEMS; REACTION PRODUCT OF 4-HALO-1,8-NAPHTHALIC ANHYDRIDE AND ETHERAMINE MILLIKEN & COMPANY (US) 1999-06-29 US claimed
WO-1998031752-A1 NAPHTHALIMIDE DYES AND THEIR USE AS FLUID VISUALIZING AGENTS MICROBIOMED CORPORATION (US) 1998-07-23 WO claimed
US-5663029-A DEVELOPMENT OF LATENT IMAGE, TRANSFERRING TO FORM RECORDING SHEETS, COATING A SUBSTRATE USING POLYMERS XEROX CORPORATION (US) 1997-09-02 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040215022-A1 Colorant compositions ARSA, TST, IK TYMS 3644/4885KDM4E 1729/4885ALDH1A1 1311/4885
US-20040215038-A1 Colorant precursor compositions RB1, SULT1A1, CBR1 TYMS 2832/4885KDM4E 2026/4885ALDH1A1 199/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.