Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | SNCA | P37840 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24439558 | 0.69 | NOX1 (0.67) | MAPK1CYP3A4TSHRMAPTALDH1A1 | |
| SCHEMBL10532249 | 0.67 | MAOA (0.49) | MAPK1CYP3A4MAPTALDH1A1LMNA | |
| SCHEMBL14606163 | 0.65 | — | — | |
| SCHEMBL3292670 | 0.64 | NOX1 (0.65) | MAPK1CYP3A4MAPTALDH1A1KDM4E | |
| SCHEMBL14467552 | 0.64 | HPGD (0.42) | MAPK1CYP3A4TSHRMAPTALDH1A1 | |
| SCHEMBL11427006 | 0.64 | CYP3A4 (0.35) | MAPK1CYP3A4TSHRALDH1A1KDM4E | |
| SCHEMBL14433978 | 0.63 | EPHX2 (0.62) | MAPK1MAPTALDH1A1KDM4ELMNA | |
| SCHEMBL11765386 | 0.63 | NOX1 (0.36) | MAPK1CYP3A4MAPTLMNASNCA | |
| SCHEMBL18913249 | 0.56 | ALDH1A1 (0.35) | TSHRALDH1A1NOX1 | |
| SCHEMBL24255127 | 0.56 | MAPT (0.50) | MAPK1CYP3A4TSHRMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5593993-A | VIRICIDES FOR HTLV TREATMENT OF AIDS | MEDIVIR AB (SE) | 1997-01-14 | — | — | US | disclosed |