Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 3/20 | 0.60 |
| ▸ | DRD2 | P14416 | 5/20 | 0.55 |
| ▸ | DRD4 | P21917 | 4/20 | 0.55 |
| ▸ | XIAP | P98170 | 2/20 | 0.53 |
| ▸ | BIRC2 | Q13490 | 2/20 | 0.53 |
| ▸ | HTR2A | P28223 | 3/20 | 0.46 |
| ▸ | HTR2C | P28335 | 3/20 | 0.46 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.46 |
| ▸ | HTR2B | P41595 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8901483 | 0.85 | NOTUM (0.65) | NOTUMDRD2DRD4XIAPBIRC2 | |
| SCHEMBL8895360 | 0.79 | NOTUM (0.68) | NOTUMDRD2DRD4XIAPBIRC2 | |
| SCHEMBL11224906 | 0.79 | NOTUM (0.68) | NOTUMDRD2DRD4XIAPBIRC2 | |
| SCHEMBL6966671 | 0.77 | NOTUM (0.64) | NOTUMDRD2DRD4XIAPBIRC2 | |
| SCHEMBL5793078 | 0.76 | NOTUM (1.00) | NOTUMDRD2DRD4XIAPBIRC2 | |
| SCHEMBL5795715 | 0.76 | NOTUM (1.00) | NOTUMDRD2DRD4XIAPBIRC2 | |
| SCHEMBL4111792 | 0.74 | NOTUM (0.73) | NOTUMDRD2DRD4XIAPBIRC2 | |
| SCHEMBL21425060 | 0.74 | NOTUM (0.73) | NOTUMDRD2DRD4XIAPBIRC2 | |
| SCHEMBL16600474 | 0.73 | NOTUM (0.71) | NOTUMDRD2DRD4XIAPBIRC2 | |
| SCHEMBL20348525 | 0.72 | NOTUM (0.70) | NOTUMDRD2DRD4XIAPBIRC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997045408-A1 | HERBICIDAL INDOLINES | ZENECA LIMITED (GB) | 1997-12-04 | — | — | WO | disclosed |