Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | CTSL | P07711 | 3/20 | 0.35 |
| ▸ | CTSB | P07858 | 3/20 | 0.35 |
| ▸ | CTSS | P25774 | 3/20 | 0.35 |
| ▸ | CTSK | P43235 | 2/20 | 0.35 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.34 |
| ▸ | SYK | P43405 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | CASP3 | P42574 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8714483 | 0.94 | MEN1 (0.35) | MEN1KMT2ACTSLCTSBCTSS | |
| SCHEMBL8893922 | 0.93 | MEN1 (0.37) | MEN1KMT2ACTSLCTSBCTSS | |
| SCHEMBL8893215 | 0.88 | KMT2A (0.33) | MEN1KMT2A | |
| SCHEMBL8707726 | 0.86 | MEN1 (0.37) | MEN1KMT2ACTSLCTSBCTSS | |
| SCHEMBL8708604 | 0.84 | MEN1 (0.33) | MEN1KMT2ACTSLCTSBCTSS | |
| SCHEMBL8896032 | 0.80 | KMT2A (0.36) | MEN1KMT2ACTSLCTSBCTSS | |
| SCHEMBL8893105 | 0.79 | MEN1 (0.36) | MEN1KMT2ACTSLCTSBCTSS | |
| SCHEMBL8894245 | 0.76 | CTSD (0.33) | MEN1KMT2ACTSLCTSBCTSS | |
| SCHEMBL9068141 | 0.76 | MEN1 (0.36) | MEN1KMT2ACTSLCTSBCTSS | |
| SCHEMBL8707602 | 0.72 | CTSS (0.30) | CTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5624897-A | PARASITICIDES, NEMATOSIDES OF CYCLIC PEPTIDE LACTONES FOR VETERINARY MEDICINE | BAYER AKTIENGESELLSCHAFT (DE) | 1997-04-29 | — | — | US | disclosed |