Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB11 | O95342 | 3/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.57 |
| ▸ | DRD1 | P21728 | 3/20 | 0.57 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.57 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.57 |
| ▸ | CYP2B6 | P20813 | 2/20 | 0.57 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.57 |
| ▸ | HTR2B | P41595 | 2/20 | 0.57 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.57 |
| ▸ | THRB | P10828 | 1/20 | 0.57 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.57 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.57 |
| ▸ | HTR2A | P28223 | 1/20 | 0.57 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.57 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | DRD4 | P21917 | 2/20 | 0.47 |
| ▸ | DRD3 | P35462 | 2/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29674909 | 1.00 | ABCB11 (0.57) | ABCB11CYP2C19DRD1OPRM1ADRA2A | |
| SCHEMBL7025224 | 1.00 | ABCB11 (0.57) | ABCB11CYP2C19DRD1OPRM1ADRA2A | |
| SCHEMBL6424678 | 0.82 | OPRL1 (0.44) | ABCB11CYP2C19DRD1OPRM1ADRA2A | |
| SCHEMBL12604040 | 0.81 | DRD1 (0.64) | ABCB11CYP2C19DRD1OPRM1ADRA2A | |
| SCHEMBL10952840 | 0.81 | DRD1 (0.64) | ABCB11CYP2C19DRD1OPRM1ADRA2A | |
| SCHEMBL16706904 | 0.81 | DRD1 (0.64) | ABCB11CYP2C19DRD1OPRM1ADRA2A | |
| Water SCHEMBL1989477 | 0.79 | ABCB11 (0.76) | ABCB11CYP2C19DRD1OPRM1ADRA2A | |
| Water SCHEMBL3377943 | 0.79 | ABCB11 (0.76) | ABCB11CYP2C19DRD1OPRM1ADRA2A | |
| SCHEMBL2721278 | 0.79 | ABCB11 (0.58) | ABCB11CYP2C19DRD1OPRM1ADRA2A | |
| Hydrochloric Acid SCHEMBL7479212 | 0.78 | ABCB11 (0.74) | ABCB11CYP2C19DRD1OPRM1ADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104045652-A | Preparation method of clopidogrel intermediate compound | JIANFENG SHEN | 2014-09-17 | — | — | CN | claimed |
| CN-100338068-C | Process for preparing clopidogrel | CADILA HEALTHCARE LTD (IN) | 2007-09-19 | — | — | CN | claimed |
| EP-1353928-B1 | PROCESS FOR PREPARING CLOPIDOGREL | CADILA HEALTHCARE LTD (IN) | 2006-12-27 | — | — | EP | claimed |
| US-20050049415-A1 | Process for preparing enantiomerically pure alpha phenyl-alpha (6,7-dihydro-4h-thieno[3,2-c]pyridin-5-yl)-acetic acid derivatives | MERCK GENERICS (UK) LIMITED (GB) | 2005-03-03 | — | — | US | claimed |
| EP-1438314-A1 | A PROCESS FOR PREPARING ENANTIOMERICALLY PURE ALPHA-PHENYL-APLPHA(6,7-DIHYDRO-4H-THIENO 3,2-C PYRIDIN-5-YL)-ACETIC ACID DERIVATIVES | Merck Generics (UK) Limited (GB) | 2004-07-21 | — | — | EP | claimed |
| CN-1487943-A | Process for preparing clopidogrel | — | 2004-04-07 | — | — | CN | claimed |
| EP-1353928-A2 | PROCESS FOR PREPARING CLOPIDOGREL | CADILA HEALTHCARE LTD. (IN) | 2003-10-22 | — | — | EP | claimed |
| US-6635763-B2 | From 2-chlorobenzaldehyde and cyanide compound, then amine; resolution of racemic mixture | CADILA HEALTH CARE LIMITED (IN) | 2003-10-21 | — | — | US | claimed |
| WO-2003035652-A1 | A PROCESS FOR PREPARING ENANTIOMERICALLY PURE α-PHENYL-α-(6,7-DIHYDRO-4H-THIENO[3,2-C]PYRIDIN-5-YL)-ACETIC ACID DERIVATIVES | MERCK GENERICS [UK] LIMITED (GB) | 2003-05-01 | — | — | WO | claimed |
| US-20020177712-A1 | Process to prepare clopidogrel | CADILA HEALTHCARE LIMITED (IN) | 2002-11-28 | — | — | US | claimed |
| WO-2002059128-A2 | PROCESS FOR PREPARING CLOPIDOGREL | CADILA HEALTHCARE LTD. (IN) | 2002-08-01 | — | — | WO | claimed |
| US-20160130227-A1 | PRODRUGS OF ANTI-PLATELET AGENTS | CELLIX BIO PRIVATE LTD (IN) | 2016-05-12 | — | — | US | disclosed |
| US-20160130227-A1 | PRODRUGS OF ANTI-PLATELET AGENTS | CELLIX BIO PRIVATE LTD (IN) | 2016-05-12 | — | — | US | disclosed |
| EP-1837337-B1 | Novel crystalline polymorphs of clopidogrel | GENERICS UK LTD (GB) | 2016-04-06 | — | — | EP | disclosed |
| US-9175008-B1 | Prodrugs of anti-platelet agents | CELLIX BIO PRIVATE LIMITED (IN) | 2015-11-03 | — | — | US | disclosed |
| EP-1353928-A2 | PROCESS FOR PREPARING CLOPIDOGREL | CADILA HEALTHCARE LTD. (IN) | 2003-10-22 | — | — | EP | disclosed |
| US-6635763-B2 | From 2-chlorobenzaldehyde and cyanide compound, then amine; resolution of racemic mixture | CADILA HEALTH CARE LIMITED (IN) | 2003-10-21 | — | — | US | disclosed |
| WO-2003035652-A1 | A PROCESS FOR PREPARING ENANTIOMERICALLY PURE α-PHENYL-α-(6,7-DIHYDRO-4H-THIENO[3,2-C]PYRIDIN-5-YL)-ACETIC ACID DERIVATIVES | MERCK GENERICS [UK] LIMITED (GB) | 2003-05-01 | — | — | WO | disclosed |
| US-20020177712-A1 | Process to prepare clopidogrel | CADILA HEALTHCARE LIMITED (IN) | 2002-11-28 | — | — | US | disclosed |
| WO-2002059128-A2 | PROCESS FOR PREPARING CLOPIDOGREL | CADILA HEALTHCARE LTD. (IN) | 2002-08-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020177712-A1 | Process to prepare clopidogrel | PTGER3, P2RY13, P2RY4 | ABCB11 1636/4885CYP2C19 33/4885DRD1 1082/4885 |
| US-20160130227-A1 | PRODRUGS OF ANTI-PLATELET AGENTS | F12, F2, PLAT | ABCB11 87/4885CYP2C19 47/4885DRD1 4203/4885 |
| US-20050049415-A1 | Process for preparing enantiomerically pure alpha phenyl-alpha (6,7-dihydro-4h-thieno[3,2-c]pyridin-5-yl)-acetic acid derivatives | NR1H3, NR1H2, NR1H4 | ABCB11 300/4885CYP2C19 124/4885DRD1 835/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.