Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 2/20 | 0.36 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.36 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.36 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | EBP | Q15125 | 1/20 | 0.30 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8893018 | 1.00 | S1PR1 (0.36) | S1PR1S1PR3S1PR5S1PR4KMT2A | |
| SCHEMBL949468 | 0.95 | L3MBTL1 (0.36) | S1PR1S1PR3S1PR5S1PR4KMT2A | |
| SCHEMBL9357045 | 0.95 | S1PR1 (0.39) | S1PR1S1PR3S1PR5S1PR4KMT2A | |
| SCHEMBL9357038 | 0.95 | S1PR1 (0.39) | S1PR1S1PR3S1PR5S1PR4KMT2A | |
| SCHEMBL10527688 | 0.93 | S1PR1 (0.41) | S1PR1S1PR3S1PR5S1PR4KMT2A | |
| SCHEMBL28772993 | 0.93 | S1PR1 (0.41) | S1PR1S1PR3S1PR5S1PR4KMT2A | |
| SCHEMBL454182 | 0.93 | S1PR1 (0.41) | S1PR1S1PR3S1PR5S1PR4KMT2A | |
| SCHEMBL9555188 | 0.93 | S1PR1 (0.41) | S1PR1S1PR3S1PR5S1PR4KMT2A | |
| SCHEMBL456427 | 0.92 | S1PR1 (0.40) | S1PR1S1PR3S1PR5S1PR4L3MBTL1 | |
| SCHEMBL8894194 | 0.89 | BDKRB2 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5665371-A | SIDE EFFECT REDUCTION | HOERRMANN WILHELM (DE) | 1997-09-09 | — | — | US | claimed |