Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A1 | O15245 | 3/20 | 0.67 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.67 |
| ▸ | TSHR | P16473 | 3/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.63 |
| ▸ | TP53 | P04637 | 1/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.60 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.60 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.60 |
| ▸ | DNM1 | Q05193 | 5/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
| ▸ | RAD52 | P43351 | 1/20 | 0.46 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7113899 | 0.92 | SLC22A1 (0.71) | SLC22A1SLC22A2TSHRALDH1A1TP53 | |
| Tetrabuthylammonium SCHEMBL6659742 | 0.92 | SLC22A1 (0.71) | SLC22A1SLC22A2TSHRALDH1A1TP53 | |
| Hydrochloric Acid SCHEMBL10380753 | 0.89 | SLC22A1 (0.67) | SLC22A1SLC22A2TSHRALDH1A1TP53 | |
| Tetrabuthylammonium SCHEMBL29204959 | 0.89 | SLC22A1 (0.56) | SLC22A1SLC22A2TSHRALDH1A1TP53 | |
| SCHEMBL11514997 | 0.86 | SLC22A1 (0.68) | SLC22A1SLC22A2TSHRALDH1A1TP53 | |
| SCHEMBL7108842 | 0.86 | SLC22A1 (0.71) | SLC22A1SLC22A2TSHRALDH1A1TP53 | |
| Tetrabuthylammonium SCHEMBL28487535 | 0.86 | SLC22A1 (0.71) | SLC22A1SLC22A2TSHRALDH1A1TP53 | |
| Bromide SCHEMBL11147770 | 0.85 | DNM1 (0.70) | SLC22A1SLC22A2TSHRALDH1A1TP53 | |
| Bromide SCHEMBL5550574 | 0.85 | DNM1 (0.70) | SLC22A1SLC22A2TSHRALDH1A1TP53 | |
| SCHEMBL766127 | 0.85 | SLC22A1 (0.92) | SLC22A1SLC22A2TSHRALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1264792-C | Process for the preparation of a chloroketones | BRISTOL MYERS SQUIBB CO (US) | 2006-07-19 | — | — | CN | disclosed |
| CN-1466561-A | Process for the preparation of a chloroketones | ����˹�ж�-����˹˹������˾ | 2004-01-07 | — | — | CN | disclosed |
| EP-0803516-A2 | Process for controlled hydrohalogenation of copolymers of olefins and dienes and resulting polymers | LES DERIVES RESINIQUES ET TERPENIQUES (FR) | 1997-10-29 | — | — | EP | disclosed |
| US-4912171-A | Blend of addition polymer, polyhydroxy compound, organo-onium compound and acid acceptor | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1990-03-27 | — | — | US | disclosed |