Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.58 |
| ▸ | CA1 | P00915 | 3/20 | 0.53 |
| ▸ | CA2 | P00918 | 3/20 | 0.53 |
| ▸ | FABP4 | P15090 | 1/20 | 0.49 |
| ▸ | FFAR4 | Q5NUL3 | 6/20 | 0.49 |
| ▸ | FFAR1 | O14842 | 5/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.47 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 2/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.46 |
| ▸ | CA5A | P35218 | 2/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | PPARA | Q07869 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.45 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9633026 | 0.89 | PKM (0.55) | PKMCA1CA2HTTALOX5 | |
| SCHEMBL9633238 | 0.86 | IAPP (0.52) | PKMCA1CA2HTTALOX5 | |
| SCHEMBL8095827 | 0.85 | GAA (0.65) | PKMFABP4HTTGAATDP1 | |
| SCHEMBL1803678 | 0.84 | PKM (0.55) | PKMCA1CA2HTTCA9 | |
| SCHEMBL9632482 | 0.83 | PKM (0.52) | PKMCA1CA2HTTALOX5 | |
| SCHEMBL1803675 | 0.82 | PKM (0.56) | PKMCA1CA2HTTCA9 | |
| SCHEMBL10639502 | 0.82 | PKM (0.53) | PKMCA1CA2ALOX5CA9 | |
| SCHEMBL142264 | 0.82 | KDM4E (0.62) | PKMCA1CA2CYP19A1CA9 | |
| SCHEMBL8167206 | 0.81 | PKM (0.51) | PKMCA1CA2HTTCA9 | |
| SCHEMBL27593086 | 0.81 | PKM (0.51) | PKMCA1CA2HTTCA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5607976-A | ANNTIISCHEMIC AGENTS AND CARDIOVASCULAR DISORDERS | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-03-04 | — | — | US | disclosed |