Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 4/20 | 0.65 |
| ▸ | PKM | P14618 | 2/20 | 0.61 |
| ▸ | CA5A | P35218 | 1/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.60 |
| ▸ | TSHR | P16473 | 2/20 | 0.60 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.49 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.49 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | FABP4 | P15090 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | SELL | P14151 | 1/20 | 0.45 |
| ▸ | SELP | P16109 | 1/20 | 0.45 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.45 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL48765 | 0.88 | PKM (0.57) | GAAPKMCA5ATDP1TSHR | |
| SCHEMBL21598826 | 0.88 | GAA (0.65) | GAAPKMCA5ATDP1TSHR | |
| SCHEMBL30610782 | 0.88 | PKM (0.57) | GAAPKMCA5ATDP1TSHR | |
| SCHEMBL8930353 | 0.86 | CA5A (0.67) | GAAPKMCA5ATDP1TSHR | |
| SCHEMBL8893349 | 0.85 | PKM (0.58) | GAAPKMCA5ATDP1HTT | |
| SCHEMBL9724436 | 0.85 | CA5A (0.61) | GAAPKMCA5ATDP1TSHR | |
| SCHEMBL6550393 | 0.84 | PKM (0.54) | GAAPKMCA5ATDP1TSHR | |
| SCHEMBL1807384 | 0.83 | PKM (0.58) | PKMCA5AALDH1A1HTTADRA1D | |
| SCHEMBL3951669 | 0.81 | PKM (0.50) | GAAPKMCA5ATDP1TSHR | |
| SCHEMBL3945648 | 0.81 | PKM (0.50) | GAAPKMCA5ATDP1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0726250-B1 | Substituted benzenesulfonylureas and -thioureas, process for their preparation and their use in the production of pharmaceutical preparations as well as pharmaceutical preparations containing them | HOECHST AG (DE) | 2000-11-02 | — | — | EP | disclosed |
| US-5607976-A | ANNTIISCHEMIC AGENTS AND CARDIOVASCULAR DISORDERS | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-03-04 | — | — | US | disclosed |
| EP-0726250-A1 | Substituted benzenesulfonylureas and -thioureas, process for their preparation and their use in the production of pharmaceutical preparations as well as pharmaceutical preparations containing them | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-08-14 | — | — | EP | disclosed |