⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2465652 | 0.74 | — | — | |
| SCHEMBL7106599 | 0.74 | — | — | |
| SCHEMBL13678663 | 0.72 | LMNA (0.35) | — | |
| SCHEMBL11291649 | 0.72 | — | — | |
| SCHEMBL5474525 | 0.72 | — | — | |
| SCHEMBL1903711 | 0.72 | TDP1 (0.32) | — | |
| SCHEMBL28268 | 0.72 | ALDH1A1 (0.39) | — | |
| SCHEMBL97657 | 0.71 | — | — | |
| Hydrochloric Acid SCHEMBL3866987 | 0.70 | TDP1 (0.31) | — | |
| SCHEMBL5143968 | 0.70 | LMNA (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0394989-B1 | Peptide compounds, process for preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO (JP) | 1994-12-21 | — | — | EP | claimed |
| US-5164372-A | Treatment of respiratory disorders, inflammation, dermatitis | FUJISAWA PHARMACEUTICAL COMPANY, LTD. (JP) | 1992-11-17 | — | — | US | claimed |
| EP-0394989-A2 | Peptide compounds, process for preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1990-10-31 | — | — | EP | claimed |
| US-5633232-A | ANALGESIC, ANTIHISTAMINE, SKIN DISORDERS, VISION DEFECTS,ANTIINFLAMMATORY AGENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-05-27 | — | — | US | disclosed |
| US-5468731-A | Peptide compounds, a process for preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-11-21 | — | — | US | disclosed |
| US-5420297-A | Antiinflammatory agents, ophthalmic and antiarthritic agents | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-05-30 | — | — | US | disclosed |
| EP-0394989-B1 | Peptide compounds, process for preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO (JP) | 1994-12-21 | — | — | EP | disclosed |
| EP-0590152-A1 | PEPTIDES WITH TACHYKININ ANTAGONIST ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-04-06 | — | — | EP | disclosed |
| EP-0443132-B1 | Peptides having tachykinin antagonist activity, a process for preparation thereof and pharmaceutical compositions comprising the same | FUJISAWA PHARMACEUTICAL CO (JP) | 1993-12-15 | — | — | EP | disclosed |
| WO-1992022569-A1 | PEPTIDES WITH TACHYKININ ANTAGONIST ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-12-23 | — | — | WO | disclosed |
| US-5164372-A | Treatment of respiratory disorders, inflammation, dermatitis | FUJISAWA PHARMACEUTICAL COMPANY, LTD. (JP) | 1992-11-17 | — | — | US | disclosed |
| EP-0482539-A2 | Peptide compounds, processes for preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-04-29 | — | — | EP | disclosed |
| EP-0443132-A1 | Peptides having tachykinin antagonist activity, a process for preparation thereof and pharmaceutical compositions comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-08-28 | — | — | EP | disclosed |
| EP-0394989-A2 | Peptide compounds, process for preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1990-10-31 | — | — | EP | disclosed |