Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 2/20 | 0.48 |
| ▸ | TACR1 | P25103 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | ECE1 | P42892 | 1/20 | 0.47 |
| ▸ | CTSL | P07711 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9293690 | 0.88 | ACE (0.48) | ACEUSP2TACR1KDM4EMEN1 | |
| SCHEMBL27330226 | 0.88 | ACE (0.50) | ACEUSP2TACR1KDM4EMEN1 | |
| SCHEMBL8829880 | 0.88 | ACE (0.50) | ACEUSP2TACR1KDM4EMEN1 | |
| SCHEMBL8829871 | 0.86 | TACR1 (0.58) | TACR1 | |
| SCHEMBL8829867 | 0.86 | TACR1 (0.58) | TACR1 | |
| SCHEMBL6888621 | 0.86 | TACR1 (0.58) | TACR1 | |
| SCHEMBL6888466 | 0.83 | USP2 (0.47) | ACEUSP2TACR1KDM4EMEN1 | |
| SCHEMBL8700148 | 0.82 | ACE (0.51) | ACEUSP2TACR1KDM4EMEN1 | |
| SCHEMBL9613706 | 0.81 | CCKBR (0.56) | ACETACR1KDM4EMEN1ALDH1A1 | |
| SCHEMBL8894490 | 0.80 | KDM4E (0.50) | ACETACR1KDM4EMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5593967-A | Cholecystokinin antagonists, their preparation and therapeutic use | WARNER-LAMBERT COMPANY (US) | 1997-01-14 | — | — | US | disclosed |
| WO-1992004045-A1 | NOVEL CHOLECYSTOKININ ANTAGONISTS, THEIR PREPARATION AND THERAPEUTIC USE | WARNER-LAMBERT COMPANY (US) | 1992-03-19 | — | — | WO | disclosed |