Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 3/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | GABRP | O00591 | 1/20 | 0.50 |
| ▸ | GABRD | O14764 | 1/20 | 0.50 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.50 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.50 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.50 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.50 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.50 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.50 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.50 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.50 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.50 |
| ▸ | GABRE | P78334 | 1/20 | 0.50 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.50 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.50 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.50 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.50 |
| ▸ | FNTA | P49354 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8893362 | 0.90 | CCKBR (0.66) | CCKBRLMNAKMT2AMEN1TSHR | |
| SCHEMBL8893462 | 0.81 | ACE (0.50) | TACR1KMT2AMEN1TSHRACE | |
| SCHEMBL8999222 | 0.81 | CCKBR (0.54) | CCKBRLMNAMC4RTACR1KMT2A | |
| SCHEMBL8999343 | 0.80 | CCKBR (0.50) | CCKBRLMNAGABRPGABRDGABRA1 | |
| SCHEMBL27785465 | 0.79 | CCKBR (0.52) | CCKBRLMNAGABRPGABRDGABRA1 | |
| SCHEMBL8998991 | 0.78 | CCKBR (0.56) | CCKBRLMNAMC4RKMT2AMEN1 | |
| SCHEMBL8999327 | 0.78 | CCKBR (0.51) | CCKBRLMNAGABRPGABRDGABRA1 | |
| SCHEMBL8999053 | 0.78 | CCKBR (0.53) | CCKBRLMNAGABRPGABRDGABRA1 | |
| SCHEMBL8999093 | 0.78 | CCKBR (0.51) | CCKBRLMNAGABRPGABRDGABRA1 | |
| SCHEMBL8704488 | 0.77 | CCKBR (0.62) | CCKBRLMNAKMT2AMEN1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992004045-A1 | NOVEL CHOLECYSTOKININ ANTAGONISTS, THEIR PREPARATION AND THERAPEUTIC USE | WARNER-LAMBERT COMPANY (US) | 1992-03-19 | — | — | WO | disclosed |