Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.55 |
| ▸ | CTSL | P07711 | 1/20 | 0.54 |
| ▸ | ACE | P12821 | 1/20 | 0.54 |
| ▸ | MMP9 | P14780 | 1/20 | 0.53 |
| ▸ | MMP8 | P22894 | 1/20 | 0.53 |
| ▸ | MME | P08473 | 1/20 | 0.53 |
| ▸ | BRS3 | P32247 | 1/20 | 0.53 |
| ▸ | NMBR | P28336 | 1/20 | 0.53 |
| ▸ | TACR1 | P25103 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | ECE1 | P42892 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8893493 | 1.00 | LTA4H (0.55) | LTA4HCTSLACEMMP9MMP8 | |
| SCHEMBL16617939 | 0.90 | CTSL (0.65) | CTSLTACR1 | |
| SCHEMBL29960207 | 0.86 | ECE1 (0.54) | LTA4HCTSLACEMAPTECE1 | |
| SCHEMBL7141475 | 0.85 | CTSL (0.70) | LTA4HCTSLMMEECE1 | |
| SCHEMBL19412126 | 0.84 | SMN1; SMN2 (0.59) | ACEMAPTECE1 | |
| SCHEMBL19412127 | 0.84 | SMN1; SMN2 (0.59) | ACEMAPTECE1 | |
| SCHEMBL7134729 | 0.84 | ECE1 (0.57) | LTA4HCTSLACEMMEMAPT | |
| SCHEMBL7136527 | 0.83 | NMBR (0.68) | MMENMBRGAAMAPTHTT | |
| SCHEMBL23100729 | 0.83 | ECE1 (0.65) | LTA4HCTSLTACR1MAPTECE1 | |
| SCHEMBL23100728 | 0.83 | ECE1 (0.65) | LTA4HCTSLTACR1MAPTECE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5593967-A | Cholecystokinin antagonists, their preparation and therapeutic use | WARNER-LAMBERT COMPANY (US) | 1997-01-14 | — | — | US | disclosed |