Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | DRD1 | P21728 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
| ▸ | EYA2 | O00167 | 1/20 | 0.39 |
| ▸ | APP | P05067 | 1/20 | 0.39 |
| ▸ | ACE | P12821 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8893857 | 0.90 | TSHR (0.52) | TDP1ALOX15TSHRKDM4ELMNA | |
| SCHEMBL5866044 | 0.90 | TSHR (0.52) | TDP1ALOX15TSHRKDM4ELMNA | |
| SCHEMBL8893554 | 0.82 | TDP1 (0.43) | TDP1ALOX15TSHRKDM4ELMNA | |
| SCHEMBL9715182 | 0.79 | FKBP1A (0.46) | TDP1ALOX15TSHRKDM4ELMNA | |
| SCHEMBL5551298 | 0.78 | TDP1 (0.68) | TDP1ALOX15TSHRKDM4ELMNA | |
| SCHEMBL5590779 | 0.76 | TDP1 (0.64) | TDP1ALOX15TSHRKDM4ELMNA | |
| SCHEMBL1051779 | 0.75 | ALOX15 (0.44) | ALOX15TSHRKDM4ELMNAL3MBTL1 | |
| SCHEMBL15499808 | 0.70 | TDP1 (0.50) | TDP1ALOX15TSHRKDM4ELMNA | |
| SCHEMBL15499809 | 0.70 | TDP1 (0.50) | TDP1ALOX15TSHRKDM4ELMNA | |
| Edetic Acid SCHEMBL11141449 | 0.69 | TDP1 (0.74) | TDP1ALOX15TSHRKDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5681544-A | Polymer-bonded complexing agents, their complexes and conjugates, processes for their production and pharmaceutical agents containing them | SCHERING AKTIENGESELLSCHAFT (DE) | 1997-10-28 | — | — | US | disclosed |