Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 2/20 | 0.34 |
| ▸ | WDR77 | Q9BQA1 | 2/20 | 0.34 |
| ▸ | ELANE | P08246 | 1/20 | 0.34 |
| ▸ | ATF4 | P18848 | 1/20 | 0.33 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.33 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.33 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | AOC2 | O75106 | 1/20 | 0.32 |
| ▸ | CETP | P11597 | 1/20 | 0.32 |
| ▸ | DCPS | Q96C86 | 1/20 | 0.31 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.31 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.31 |
| ▸ | PDE4A | P27815 | 1/20 | 0.31 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.31 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL360662 | 0.83 | ITGB3 (0.41) | PRMT5WDR77ELANEATF4SPHK1 | |
| SCHEMBL23386552 | 0.81 | PIK3CD (0.37) | PRMT5WDR77ELANEATF4SPHK1 | |
| SCHEMBL24158596 | 0.81 | KDM4E (0.36) | PRMT5WDR77ELANEATF4SPHK1 | |
| SCHEMBL27539170 | 0.79 | SPHK1 (0.37) | ELANESPHK1KAT2BBAZ2BPDE4D | |
| SCHEMBL8105483 | 0.78 | ELANE (0.35) | PRMT5WDR77ELANEATF4SPHK1 | |
| SCHEMBL21617359 | 0.76 | PRMT5 (0.39) | PRMT5WDR77ELANEATF4SPHK1 | |
| SCHEMBL21576962 | 0.76 | PIK3CD (0.38) | PRMT5WDR77ELANEATF4SPHK1 | |
| SCHEMBL24158831 | 0.76 | KAT2B (0.42) | PRMT5WDR77ELANEATF4KAT2B | |
| SCHEMBL2094603 | 0.76 | KAT2B (0.33) | PRMT5WDR77ELANESPHK1KAT2B | |
| SCHEMBL3254867 | 0.75 | TSHR (0.42) | L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0618222-A2 | Dipeptid derivatives of 5-amino-4-hydroxy-hexanoic acid | CIBA-GEIGY AG (CH) | 1994-10-05 | — | — | EP | claimed |
| US-5643878-A | TREATMENT OF RETROVIRAL DISEASES LIKE AIDS | CIBA-GEIGY CORPORATION (US) | 1997-07-01 | — | — | US | disclosed |
| CN-1112125-A | Acyloxyhexanoic acid derivatives | CIBA GEIGY AG (CH) | 1995-11-22 | — | — | CN | disclosed |
| EP-0618222-A2 | Dipeptid derivatives of 5-amino-4-hydroxy-hexanoic acid | CIBA-GEIGY AG (CH) | 1994-10-05 | — | — | EP | disclosed |