Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.35 |
| ▸ | AOC2 | O75106 | 1/20 | 0.34 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.34 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.34 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.33 |
| ▸ | ATF4 | P18848 | 1/20 | 0.32 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.32 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | PDE4A | P27815 | 1/20 | 0.31 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.31 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.31 |
| ▸ | LTA4H | P09960 | 1/20 | 0.31 |
| ▸ | CETP | P11597 | 1/20 | 0.31 |
| ▸ | DCPS | Q96C86 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28031309 | 0.84 | — | — | |
| SCHEMBL8893566 | 0.81 | PRMT5 (0.34) | SPHK1AOC2PRMT5WDR77ELANE | |
| SCHEMBL360662 | 0.81 | ITGB3 (0.41) | SPHK1AOC2PRMT5WDR77ELANE | |
| SCHEMBL12599205 | 0.80 | — | — | |
| SCHEMBL6120762 | 0.80 | HTT (0.40) | ATF4HTT | |
| SCHEMBL2258293 | 0.80 | SPHK1 (0.39) | KDM4ESPHK1AOC2ELANEPDE4D | |
| SCHEMBL23386552 | 0.79 | PIK3CD (0.37) | SPHK1AOC2PRMT5WDR77ELANE | |
| SCHEMBL6206588 | 0.79 | SPHK1 (0.44) | KDM4ESPHK1ELANEPDE4DCYP11B2 | |
| SCHEMBL21617359 | 0.79 | PRMT5 (0.39) | KDM4ESPHK1AOC2PRMT5WDR77 | |
| SCHEMBL12599011 | 0.78 | HTT (0.39) | ATF4HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3793565-B1 | MCL-1 INHIBITORS | GILEAD SCIENCES INC (US) | 2022-01-05 | — | — | EP | disclosed |