Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | CAPN1 | P07384 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7462123 | 0.90 | ADORA2A (0.48) | ADORA2AKMT2ALMNATDP1CAPN1 | |
| SCHEMBL27505326 | 0.88 | ADORA2A (0.43) | ADORA2ATDP1CAPN1POLB | |
| SCHEMBL27563356 | 0.83 | ADORA2A (0.48) | ADORA2AKMT2ALMNATDP1POLB | |
| SCHEMBL7457111 | 0.83 | ADORA2A (0.48) | ADORA2AKMT2ALMNATDP1POLB | |
| SCHEMBL7463401 | 0.83 | ITGB3 (0.45) | ADORA2ACA2CA1NAALAD2 | |
| SCHEMBL8892198 | 0.81 | ADORA2A (0.47) | ADORA2AKMT2ALMNATDP1POLB | |
| SCHEMBL7462112 | 0.80 | ADORA2A (0.54) | ADORA2AKMT2ACA2 | |
| SCHEMBL7457527 | 0.79 | ADORA2A (0.43) | ADORA2A | |
| SCHEMBL8893137 | 0.78 | ADORA2A (0.49) | ADORA2AKMT2ATDP1MEN1 | |
| SCHEMBL7456296 | 0.77 | PRSS1 (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5614535-A | Adhesion receptor antagonists | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1997-03-25 | — | — | US | disclosed |