Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APEX1 | P27695 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | FEN1 | P39748 | 1/20 | 0.39 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | GPR17 | Q13304 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4628780 | 0.82 | APEX1 (0.47) | APEX1GLAKDM4EGRIN1GRIN2B | |
| SCHEMBL8377270 | 0.76 | KDM4E (0.64) | APEX1GLAKDM4EALDH1A1 | |
| SCHEMBL21027504 | 0.74 | GLA (0.69) | APEX1GLAKDM4EMEN1KMT2A | |
| SCHEMBL2255490 | 0.72 | MEN1 (0.62) | APEX1GLAKDM4EMEN1KMT2A | |
| SCHEMBL22904374 | 0.72 | FEN1 (0.41) | FEN1HPGD | |
| SCHEMBL8893031 | 0.71 | GRIN2D (0.48) | APEX1HDAC1HDAC8HDAC6GRIN1 | |
| SCHEMBL8890567 | 0.71 | HDAC1 (0.47) | APEX1HDAC1HDAC8HDAC6GLA | |
| SCHEMBL8890895 | 0.70 | HDAC6 (0.58) | HDAC1HDAC8HDAC6FEN1GRIN1 | |
| SCHEMBL6482979 | 0.69 | KDM4E (0.46) | APEX1HDAC1HDAC6GLAKDM4E | |
| SCHEMBL13537857 | 0.69 | MEN1 (0.47) | HDAC1HDAC8HDAC6KDM4EGRIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997002254-A1 | QUINAZOLINE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-01-23 | — | — | WO | disclosed |