Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 3/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.47 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.43 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.43 |
| ▸ | GPR17 | Q13304 | 1/20 | 0.40 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.39 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.39 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.39 |
| ▸ | GRIA1 | P42261 | 2/20 | 0.39 |
| ▸ | GRIA2 | P42262 | 2/20 | 0.39 |
| ▸ | GRIA3 | P42263 | 2/20 | 0.39 |
| ▸ | GRIA4 | P48058 | 2/20 | 0.39 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.39 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.39 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.39 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8046411 | 0.83 | MAT2A (0.52) | HDAC1HDAC8HDAC6AKR1A1AKR1B1 | |
| SCHEMBL4629626 | 0.82 | B3GNT2 (0.47) | GRIN2DGRIN3BGRIA1GRIA2GRIA3 | |
| SCHEMBL18554543 | 0.79 | PDE5A (0.46) | HDAC1HDAC8HDAC6AKR1A1AKR1B1 | |
| SCHEMBL8377270 | 0.79 | KDM4E (0.64) | AKR1B1GLAAPEX1KDM4E | |
| SCHEMBL6358211 | 0.74 | CBX7 (0.44) | AKR1A1AKR1B1 | |
| SCHEMBL21027239 | 0.74 | GLA (0.74) | GLAAPEX1KDM4E | |
| SCHEMBL21027247 | 0.73 | GLA (0.51) | AKR1A1AKR1B1EGLN1GLAKDM4E | |
| SCHEMBL14692230 | 0.72 | METAP2 (0.44) | HDAC1HDAC8HDAC6EGLN1 | |
| SCHEMBL30015488 | 0.72 | METAP2 (0.44) | HDAC1HDAC8HDAC6EGLN1 | |
| SCHEMBL411220 | 0.72 | KDM4E (0.56) | AKR1A1AKR1B1GLAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997002254-A1 | QUINAZOLINE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-01-23 | — | — | WO | disclosed |