SCHEMBL8893652

SCHEMBL8893652

NCCc1ccc(Cl)c(Cl)c1Cl

nearest known ligand 0.65

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 12/20 0.65
PNMT P11086 2/20 0.45
HTR2A P28223 1/20 0.39
MAOB P27338 2/20 0.38
CYP3A4 P08684 1/20 0.37
MAPK1 P28482 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20563034 0.80 TAAR1 (0.53) TAAR1PNMTHTR2AMAOBMAPK1
SCHEMBL2095375 0.80 PNMT (0.65) TAAR1PNMTCYP3A4MAPK1
SCHEMBL1570973 0.79 TAAR1 (1.00) TAAR1PNMTHTR2AMAOBCYP3A4
SCHEMBL30785390 0.79 TAAR1 (1.00) TAAR1PNMTHTR2AMAOBCYP3A4
SCHEMBL9482589 0.78 TAAR1 (0.40) TAAR1PNMTCYP3A4MAPK1
SCHEMBL8440317 0.76 TAAR1 (0.39) TAAR1PNMTCYP3A4MAPK1
SCHEMBL17552721 0.76 TAAR1 (0.39) TAAR1PNMTCYP3A4MAPK1
SCHEMBL10061111 0.76 TAAR1 (0.39) TAAR1PNMTCYP3A4MAPK1
SCHEMBL8310445 0.76 TAAR1 (0.48) TAAR1PNMTHTR2AMAOB
SCHEMBL4465598 0.74 CYP3A4 (0.43) TAAR1PNMTCYP3A4MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5593993-A VIRICIDES FOR HTLV TREATMENT OF AIDS MEDIVIR AB (SE) 1997-01-14 US disclosed