Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.64 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 5/20 | 0.57 |
| ▸ | GFER | P55789 | 1/20 | 0.57 |
| ▸ | NGLY1 | Q96IV0 | 1/20 | 0.57 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.51 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.51 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | IDO1 | P14902 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL432229 | 0.80 | KCNK2 (0.55) | GRIK1MAPTHSD17B10ALDH1A1HPGD | |
| SCHEMBL4311266 | 0.78 | PTPN1 (1.00) | PTPN1GRIK1MAPTGFERNGLY1 | |
| SCHEMBL5860670 | 0.78 | PTPN1 (0.70) | PTPN1GRIK1MAPTGFERNGLY1 | |
| SCHEMBL12368149 | 0.76 | MAPT (0.60) | MAPTHSD17B10KDM4EALDH1A1HPGD | |
| SCHEMBL1893876 | 0.75 | KCNK2 (0.57) | PTPN1GRIK1MAPTHSD17B10KDM4E | |
| SCHEMBL9743950 | 0.75 | GRIK1 (0.56) | GRIK1MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL2841346 | 0.75 | PTPN1 (0.66) | PTPN1GRIK1MAPTGFERNGLY1 | |
| SCHEMBL30694140 | 0.75 | SMN1; SMN2 (0.39) | PTPN1GRIK1MAPTHSD17B10KDM4E | |
| SCHEMBL16198286 | 0.74 | KDM4E (0.64) | HSD17B10KDM4EALDH1A1AKR1C3AKR1C2 | |
| SCHEMBL8550609 | 0.74 | GRIK1 (0.56) | GRIK1GFERMEN1KMT2ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997014685-A1 | PYRIMIDINE DERIVATIVES | GYÓGYSZERKUTATÓ INTÉZET KFT (HU) | 1997-04-24 | — | — | WO | disclosed |