Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.68 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | SLC1A3 | P43003 | 3/20 | 0.38 |
| ▸ | SLC1A2 | P43004 | 3/20 | 0.38 |
| ▸ | SLC1A1 | P43005 | 3/20 | 0.38 |
| ▸ | MIF | P14174 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | PARP15 | Q460N3 | 2/20 | 0.36 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | THRA | P10827 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | KLK7 | P49862 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8896080 | 1.00 | LMNA (0.68) | LMNAPOLBALDH1A1SLC1A3SLC1A2 | |
| SCHEMBL8894738 | 0.98 | LMNA (0.65) | LMNAPOLBALDH1A1SLC1A3SLC1A2 | |
| SCHEMBL8894215 | 0.89 | LMNA (0.64) | LMNAPOLBALDH1A1SLC1A3SLC1A2 | |
| SCHEMBL8894452 | 0.89 | LMNA (0.64) | LMNAPOLBALDH1A1SLC1A3SLC1A2 | |
| SCHEMBL9208258 | 0.88 | LMNA (0.85) | LMNAPOLBALDH1A1SLC1A3SLC1A2 | |
| SCHEMBL8893481 | 0.87 | LMNA (0.62) | LMNAPOLBALDH1A1SLC1A3SLC1A2 | |
| SCHEMBL8895320 | 0.87 | LMNA (0.62) | LMNAPOLBALDH1A1SLC1A3SLC1A2 | |
| SCHEMBL8895826 | 0.87 | LMNA (0.61) | LMNAPOLBALDH1A1SLC1A3SLC1A2 | |
| SCHEMBL8894179 | 0.86 | LMNA (0.60) | LMNAPOLBALDH1A1GAA | |
| SCHEMBL8895240 | 0.86 | LMNA (0.60) | LMNAPOLBALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5670563-A | ORGANOTIN COMPOUND, PHOSPHORUS COMPOUND | CIBA-SPECIALTY CHEMICALS CORPORATION (US) | 1997-09-23 | — | — | US | disclosed |